Publications

  1. Kachuri, L, Hoffmann, TJ, Jiang, Y, Berndt, SI, Shelley, JP, Schaffer, KR et al.. Author Correction: Genetically adjusted PSA levels for prostate cancer screening. Nat Med. 2025; :. doi: 10.1038/s41591-025-03539-4. PubMed PMID:39901049 .
  2. Acuna, N, Park, SY, Conti, DV, Stern, MC, Wu, AH, Cheng, I et al.. Circulating microRNAs and alcohol consumption in the Multiethnic Cohort Study. Alcohol. 2025; :. doi: 10.1016/j.alcohol.2025.01.007. PubMed PMID:39880058 .
  3. Patterson, WB, Young, ND, Holzhausen, EA, Lurmann, F, Liang, D, Walker, DI et al.. Oxidative gaseous air pollutant exposure interacts with PNPLA3-I148M genotype to influence liver fat fraction and multi-omics profiles in young adults. Environ Pollut. 2025;368 :125692. doi: 10.1016/j.envpol.2025.125692. PubMed PMID:39864653 .
  4. Stratakis, N, Anguita-Ruiz, A, Fabbri, L, Maitre, L, González, JR, Andrusaityte, S et al.. Multi-omics architecture of childhood obesity and metabolic dysfunction uncovers biological pathways and prenatal determinants. Nat Commun. 2025;16 (1):654. doi: 10.1038/s41467-025-56013-7. PubMed PMID:39809770 PubMed Central PMC11732992.
  5. Beglarian, E, Chen, JC, Li, Z, Costello, E, Wang, H, Hampson, H et al.. Proteins and pathways involved in inflammation are longitudinally associated with total body bone mineral density among primarily hispanic overweight/obese adolescents and young adults. J Bone Miner Res. 2025; :. doi: 10.1093/jbmr/zjaf002. PubMed PMID:39808688 .
  6. Li, S, Oliva, P, Zhang, L, Goodrich, JA, McConnell, R, Conti, DV et al.. Associations between per-and polyfluoroalkyl substances (PFAS) and county-level cancer incidence between 2016 and 2021 and incident cancer burden attributable to PFAS in drinking water in the United States. J Expo Sci Environ Epidemiol. 2025; :. doi: 10.1038/s41370-024-00742-2. PubMed PMID:39789195 .
  7. Reiner, AS, Watt, GP, Malone, KE, Lynch, CF, John, EM, Knight, JA et al.. Breast Cancer Susceptibility Gene Sequence Variations and Development of Contralateral Breast Cancer. JAMA Netw Open. 2024;7 (12):e2452158. doi: 10.1001/jamanetworkopen.2024.52158. PubMed PMID:39786405 PubMed Central PMC11686411.
  8. Goss, LB, Liu, M, Zheng, Y, Guo, B, Conti, DV, Haiman, CA et al.. Polygenic Risk Score and Upgrading in Patients With Prostate Cancer Receiving Active Surveillance. JAMA Oncol. 2024; :. doi: 10.1001/jamaoncol.2024.5398. PubMed PMID:39666350 .
  9. Huang, X, Lott, PC, Hu, D, Zavala, VA, Jamal, ZN, Vidaurre, T et al.. Evaluation of Multiple Breast Cancer Polygenic Risk Score Panels in Women of Latin American Heritage. Cancer Epidemiol Biomarkers Prev. 2025;34 (2):234-245. doi: 10.1158/1055-9965.EPI-24-1247. PubMed PMID:39625644 PubMed Central PMC11799839.
  10. Kullo, IJ, Conomos, MP, Nelson, SC, Adebamowo, SN, Choudhury, A, Conti, D et al.. The PRIMED Consortium: Reducing disparities in polygenic risk assessment. Am J Hum Genet. 2024;111 (12):2594-2606. doi: 10.1016/j.ajhg.2024.10.010. PubMed PMID:39561770 PubMed Central PMC11639095.
  11. Li, S, Goodrich, JA, Costello, E, Walker, DI, Cardenas-Iniguez, C, Chen, JC et al.. Examining disparities in PFAS plasma concentrations: Impact of drinking water contamination, food access, proximity to industrial facilities and superfund sites. Environ Res. 2025;264 (Pt 1):120370. doi: 10.1016/j.envres.2024.120370. PubMed PMID:39549910 PubMed Central PMC11631652.
  12. Li, S, Goodrich, JA, Chen, JC, Costello, E, Beglarian, E, Liao, J et al.. Per-and polyfluoroalkyl substances and disrupted sleep: mediating roles of proteins. Environ Adv. 2024;17 :. doi: 10.1016/j.envadv.2024.100585. PubMed PMID:39512894 PubMed Central PMC11542765.
  13. McGee, HM, Bonner, JD, Egelston, C, Fu, Y, Flores, OC, Lindsey, S et al.. Genetic Variation and Regulation of MICA Alters Natural Killer Cell-Mediated Immunosurveillance in Early-Onset Colorectal Cancer. medRxiv. 2024; :. doi: 10.1101/2024.09.22.24314127. PubMed PMID:39464256 PubMed Central PMC11507956.
  14. Hampson, HE, Li, S, Walker, DI, Wang, H, Jia, Q, Rock, S et al.. The potential mediating role of the gut microbiome and metabolites in the association between PFAS and kidney function in young adults: A proof-of-concept study. Sci Total Environ. 2024;954 :176519. doi: 10.1016/j.scitotenv.2024.176519. PubMed PMID:39424468 PubMed Central PMC11731310.
  15. Liu, S, Zhu, J, Zhong, H, Wu, C, Xue, H, Darst, BF et al.. Identification of proteins associated with type 2 diabetes risk in diverse racial and ethnic populations. Diabetologia. 2024;67 (12):2754-2770. doi: 10.1007/s00125-024-06277-3. PubMed PMID:39349773 .
  16. Thomas, CE, Lin, Y, Kim, M, Kawaguchi, ES, Qu, C, Um, CY et al.. Characterization of Additive Gene-environment Interactions For Colorectal Cancer Risk. Epidemiology. 2025;36 (1):126-138. doi: 10.1097/EDE.0000000000001795. PubMed PMID:39316822 .
  17. Pan, S, Li, Z, Rubbo, B, Quon-Chow, V, Chen, JC, Baumert, BO et al.. Applications of mixture methods in epidemiological studies investigating the health impact of persistent organic pollutants exposures: a scoping review. J Expo Sci Environ Epidemiol. 2024; :. doi: 10.1038/s41370-024-00717-3. PubMed PMID:39256588 .
  18. Zhao, Y, Jia, Q, Goodrich, J, Darst, B, Conti, DV. An extension of latent unknown clustering integrating multi-omics data (LUCID) incorporating incomplete omics data. Bioinform Adv. 2024;4 (1):vbae123. doi: 10.1093/bioadv/vbae123. PubMed PMID:39224838 PubMed Central PMC11368387.
  19. Goodrich, JA, Wang, H, Jia, Q, Stratakis, N, Zhao, Y, Maitre, L et al.. Integrating Multi-Omics with environmental data for precision health: A novel analytic framework and case study on prenatal mercury induced childhood fatty liver disease. Environ Int. 2024;190 :108930. doi: 10.1016/j.envint.2024.108930. PubMed PMID:39128376 PubMed Central PMC11620538.
  20. Baumert, BO, Maretti-Mira, AC, Li, Z, Stratakis, N, Zhao, Y, Walker, DI et al.. PFHpA alters lipid metabolism and increases the risk of metabolic dysfunction-associated steatotic liver disease in youth-a translational research framework. medRxiv. 2024; :. doi: 10.1101/2024.07.01.24309775. PubMed PMID:39006440 PubMed Central PMC11245066.
  21. Plym, A, Zhang, Y, Stopsack, KH, Ugalde-Morales, E, Seibert, TM, Conti, DV et al.. Early Prostate Cancer Deaths Among Men With Higher vs Lower Genetic Risk. JAMA Netw Open. 2024;7 (7):e2420034. doi: 10.1001/jamanetworkopen.2024.20034. PubMed PMID:38958976 PubMed Central PMC11222990.
  22. Li, Y, Baumert, BO, Stratakis, N, Goodrich, JA, Wu, H, Liu, SH et al.. Exposure to per- and polyfluoroalkyl substances and alterations in plasma microRNA profiles in children. Environ Res. 2024;259 :119496. doi: 10.1016/j.envres.2024.119496. PubMed PMID:38936497 .
  23. Jiang, L, Shen, J, Darst, BF, Haiman, CA, Mancuso, N, Conti, DV et al.. Hierarchical joint analysis of marginal summary statistics-Part II: High-dimensional instrumental analysis of omics data. Genet Epidemiol. 2024;48 (7):291-309. doi: 10.1002/gepi.22577. PubMed PMID:38887957 .
  24. Chen, DM, Dong, R, Kachuri, L, Hoffmann, TJ, Jiang, Y, Berndt, SI et al.. Transcriptome-wide association analysis identifies candidate susceptibility genes for prostate-specific antigen levels in men without prostate cancer. HGG Adv. 2024;5 (3):100315. doi: 10.1016/j.xhgg.2024.100315. PubMed PMID:38845201 PubMed Central PMC11262184.
  25. Drew, DA, Kim, AE, Lin, Y, Qu, C, Morrison, J, Lewinger, JP et al.. Two genome-wide interaction loci modify the association of nonsteroidal anti-inflammatory drugs with colorectal cancer. Sci Adv. 2024;10 (22):eadk3121. doi: 10.1126/sciadv.adk3121. PubMed PMID:38809988 PubMed Central PMC11135391.
  26. Papadimitriou, N, Kim, A, Kawaguchi, ES, Morrison, J, Diez-Obrero, V, Albanes, D et al.. Genome-wide interaction study of dietary intake of fibre, fruits, and vegetables with risk of colorectal cancer. EBioMedicine. 2024;104 :105146. doi: 10.1016/j.ebiom.2024.105146. PubMed PMID:38749303 PubMed Central PMC11112268.
  27. Baumert, BO, Wang, H, Samy, S, Park, SK, Lam, CN, Dunn, K et al.. Environmental pollutant risk factors for worse COVID-19 related clinical outcomes in predominately hispanic and latino populations. Environ Res. 2024;252 (Pt 4):119072. doi: 10.1016/j.envres.2024.119072. PubMed PMID:38729411 PubMed Central PMC11198996.
  28. Baumert, BO, Eckel, SP, Goodrich, JA, Li, Z, Stratakis, N, Walker, DI et al.. Changes in plasma concentrations of per- and Polyfluoroalkyl substances after bariatric surgery in adolescents from the Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) study. Sci Total Environ. 2024;930 :172840. doi: 10.1016/j.scitotenv.2024.172840. PubMed PMID:38685432 PubMed Central PMC11103488.
  29. Chen, Z, Guo, X, Tao, R, Huyghe, JR, Law, PJ, Fernandez-Rozadilla, C et al.. Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes. Nat Commun. 2024;15 (1):3557. doi: 10.1038/s41467-024-47399-x. PubMed PMID:38670944 PubMed Central PMC11053150.
  30. Shen, J, Jiang, L, Wang, K, Wang, A, Chen, F, Newcombe, PJ et al.. Hierarchical joint analysis of marginal summary statistics-Part I: Multipopulation fine mapping and credible set construction. Genet Epidemiol. 2024;48 (6):241-257. doi: 10.1002/gepi.22562. PubMed PMID:38606643 .
  31. Tian, Y, Lin, Y, Qu, C, Arndt, V, Baurley, JW, Berndt, SI et al.. Genetic risk impacts the association of menopausal hormone therapy with colorectal cancer risk. Br J Cancer. 2024;130 (10):1687-1696. doi: 10.1038/s41416-024-02638-2. PubMed PMID:38561434 PubMed Central PMC11091089.
  32. Chen, JC, Goodrich, JA, Walker, DI, Liao, J, Costello, E, Alderete, TL et al.. Exposure to per- and polyfluoroalkyl substances and high-throughput proteomics in Hispanic youth. Environ Int. 2024;186 :108601. doi: 10.1016/j.envint.2024.108601. PubMed PMID:38537583 PubMed Central PMC11479670.
  33. Rubbo, B, Li, Z, Tachachartvanich, P, Baumert, BO, Wang, H, Pan, S et al.. Exposure to 4,4'-DDE in visceral adipose tissue and weight loss in adolescents from the Teen-LABS cohort. Obesity (Silver Spring). 2024;32 (5):1023-1032. doi: 10.1002/oby.24009. PubMed PMID:38515392 PubMed Central PMC11039378.
  34. Hou, K, Gogarten, S, Kim, J, Hua, X, Dias, JA, Sun, Q et al.. Admix-kit: an integrated toolkit and pipeline for genetic analyses of admixed populations. Bioinformatics. 2024;40 (4):. doi: 10.1093/bioinformatics/btae148. PubMed PMID:38490256 PubMed Central PMC10980565.
  35. Saunders, EJ, Dadaev, T, Brook, MN, Wakerell, S, Govindasami, K, Rageevakumar, R et al.. Identification of Genes with Rare Loss of Function Variants Associated with Aggressive Prostate Cancer and Survival. Eur Urol Oncol. 2024;7 (2):248-257. doi: 10.1016/j.euo.2024.02.003. PubMed PMID:38458890 .
  36. Plym, A, Madueke, I, Naik, S, Isabelle, M, Conti, DV, Haiman, CA et al.. Combining magnetic resonance imaging with a multi-ancestry polygenic risk score to improve identification of clinically significant prostate cancer. JNCI Cancer Spectr. 2024;8 (2):. doi: 10.1093/jncics/pkae014. PubMed PMID:38429995 PubMed Central PMC10980589.
  37. Chung, MK, House, JS, Akhtari, FS, Makris, KC, Langston, MA, Islam, KT et al.. Decoding the exposome: data science methodologies and implications in exposome-wide association studies (ExWASs). Exposome. 2024;4 (1):osae001. doi: 10.1093/exposome/osae001. PubMed PMID:38344436 PubMed Central PMC10857773.
  38. Costello, E, Goodrich, JA, Patterson, WB, Walker, DI, Chen, JC, Baumert, BO et al.. Proteomic and Metabolomic Signatures of Diet Quality in Young Adults. Nutrients. 2024;16 (3):. doi: 10.3390/nu16030429. PubMed PMID:38337712 PubMed Central PMC10857402.
  39. Hampson, HE, Costello, E, Walker, DI, Wang, H, Baumert, BO, Valvi, D et al.. Associations of dietary intake and longitudinal measures of per- and polyfluoroalkyl substances (PFAS) in predominantly Hispanic young Adults: A multicohort study. Environ Int. 2024;185 :108454. doi: 10.1016/j.envint.2024.108454. PubMed PMID:38316574 PubMed Central PMC11089812.
  40. Li, YJ, Baumert, BO, Stratakis, N, Goodrich, JA, Wu, HT, He, JX et al.. Circulating microRNA expression and nonalcoholic fatty liver disease in adolescents with severe obesity. World J Gastroenterol. 2024;30 (4):332-345. doi: 10.3748/wjg.v30.i4.332. PubMed PMID:38313232 PubMed Central PMC10835537.
  41. Yarmolinsky, J, Robinson, JW, Mariosa, D, Karhunen, V, Huang, J, Dimou, N et al.. Association between circulating inflammatory markers and adult cancer risk: a Mendelian randomization analysis. EBioMedicine. 2024;100 :104991. doi: 10.1016/j.ebiom.2024.104991. PubMed PMID:38301482 PubMed Central PMC10844944.
  42. Ochs-Balcom, HM, Preus, L, Du, Z, Elston, RC, Teerlink, CC, Jia, G et al.. Novel breast cancer susceptibility loci under linkage peaks identified in African ancestry consortia. Hum Mol Genet. 2024;33 (8):687-697. doi: 10.1093/hmg/ddae002. PubMed PMID:38263910 PubMed Central PMC11000665.
  43. Stern, MC, Sanchez Mendez, J, Kim, AE, Obón-Santacana, M, Moratalla-Navarro, F, Martín, V et al.. Genome-Wide Gene-Environment Interaction Analyses to Understand the Relationship between Red Meat and Processed Meat Intake and Colorectal Cancer Risk. Cancer Epidemiol Biomarkers Prev. 2024;33 (3):400-410. doi: 10.1158/1055-9965.EPI-23-0717. PubMed PMID:38112776 PubMed Central PMC11343583.
  44. Beglarian, E, Costello, E, Walker, DI, Wang, H, Alderete, TL, Chen, Z et al.. Exposure to perfluoroalkyl substances and longitudinal changes in bone mineral density in adolescents and young adults: A multi-cohort study. Environ Res. 2024;244 :117611. doi: 10.1016/j.envres.2023.117611. PubMed PMID:38061983 PubMed Central PMC10922273.
  45. Watts, EL, Gonzales, TI, Strain, T, Saint-Maurice, PF, Bishop, DT, Chanock, SJ et al.. Observational and genetic associations between cardiorespiratory fitness and cancer: a UK Biobank and international consortia study. Br J Cancer. 2024;130 (1):114-124. doi: 10.1038/s41416-023-02489-3. PubMed PMID:38057395 PubMed Central PMC10781786.
  46. Li, Y, Baumert, BO, Costello, E, Chen, JC, Rock, S, Stratakis, N et al.. Per- and polyfluoroalkyl substances, polychlorinated biphenyls, organochlorine pesticides, and polybrominated diphenyl ethers and dysregulation of MicroRNA expression in humans and animals-A systematic review. Environ Res. 2024;244 :117832. doi: 10.1016/j.envres.2023.117832. PubMed PMID:38056610 PubMed Central PMC10932823.
  47. Hughley, RW, Matejcic, M, Song, Z, Sheng, X, Wan, P, Xia, L et al.. Polygenic Risk Score Modifies Prostate Cancer Risk of Pathogenic Variants in Men of African Ancestry. Cancer Res Commun. 2023;3 (12):2544-2550. doi: 10.1158/2767-9764.CRC-23-0022. PubMed PMID:38014910 PubMed Central PMC10720390.
  48. Goodrich, JA, Wang, H, Walker, DI, Lin, X, Hu, X, Alderete, TL et al.. Postprandial Metabolite Profiles and Risk of Prediabetes in Young People: A Longitudinal Multicohort Study. Diabetes Care. 2024;47 (1):151-159. doi: 10.2337/dc23-0327. PubMed PMID:37971952 PubMed Central PMC10733648.
  49. Hoffmann, TJ, Graff, RE, Madduri, RK, Rodriguez, AA, Cario, CL, Feng, K et al.. Genome-wide association study of prostate-specific antigen levels in 392,522 men identifies new loci and improves cross-ancestry prediction. medRxiv. 2024; :. doi: 10.1101/2023.10.27.23297676. PubMed PMID:37961155 PubMed Central PMC10635224.
  50. Wang, A, Shen, J, Rodriguez, AA, Saunders, EJ, Chen, F, Janivara, R et al.. Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants. Nat Genet. 2023;55 (12):2065-2074. doi: 10.1038/s41588-023-01534-4. PubMed PMID:37945903 PubMed Central PMC10841479.
  51. Bogumil, D, Stram, D, Preston, DL, Pandol, SJ, Wu, AH, McKean-Cowdin, R et al.. Excess pancreatic cancer risk due to smoking and modifying effect of quitting smoking: The Multiethnic Cohort Study. Cancer Causes Control. 2024;35 (3):541-548. doi: 10.1007/s10552-023-01811-x. PubMed PMID:37924460 PubMed Central PMC10838846.
  52. Chan, TF, Rui, X, Conti, DV, Fornage, M, Graff, M, Haessler, J et al.. Estimating heritability explained by local ancestry and evaluating stratification bias in admixture mapping from summary statistics. Am J Hum Genet. 2023;110 (11):1853-1862. doi: 10.1016/j.ajhg.2023.09.012. PubMed PMID:37875120 PubMed Central PMC10645552.
  53. Chen, JC, Baumert, BO, Li, Y, Li, Y, Pan, S, Robinson, S et al.. Associations of per- and polyfluoroalkyl substances, polychlorinated biphenyls, organochlorine pesticides, and polybrominated diphenyl ethers with oxidative stress markers: A systematic review and meta-analysis. Environ Res. 2023;239 (Pt 1):117308. doi: 10.1016/j.envres.2023.117308. PubMed PMID:37813138 PubMed Central PMC10841434.
  54. Thomas, M, Su, YR, Rosenthal, EA, Sakoda, LC, Schmit, SL, Timofeeva, MN et al.. Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations. Nat Commun. 2023;14 (1):6147. doi: 10.1038/s41467-023-41819-0. PubMed PMID:37783704 PubMed Central PMC10545678.
  55. Baumert, BO, Fischer, FC, Nielsen, F, Grandjean, P, Bartell, S, Stratakis, N et al.. Paired Liver:Plasma PFAS Concentration Ratios from Adolescents in the Teen-LABS Study and Derivation of Empirical and Mass Balance Models to Predict and Explain Liver PFAS Accumulation. Environ Sci Technol. 2023;57 (40):14817-14826. doi: 10.1021/acs.est.3c02765. PubMed PMID:37756184 PubMed Central PMC10591710.
  56. Darst, BF, Saunders, E, Dadaev, T, Sheng, X, Wan, P, Pooler, L et al.. Germline Sequencing Analysis to Inform Clinical Gene Panel Testing for Aggressive Prostate Cancer. JAMA Oncol. 2023;9 (11):1514-1524. doi: 10.1001/jamaoncol.2023.3482. PubMed PMID:37733366 PubMed Central PMC10881219.
  57. Patterson, WB, Holzhausen, E, Chalifour, B, Goodrich, J, Costello, E, Lurmann, F et al.. Exposure to ambient air pollutants, serum miRNA networks, lipid metabolism, and non-alcoholic fatty liver disease in young adults. Ecotoxicol Environ Saf. 2023;264 :115486. doi: 10.1016/j.ecoenv.2023.115486. PubMed PMID:37729806 PubMed Central PMC10548742.
  58. Berndt, SI, Vijai, J, Benavente, Y, Camp, NJ, Nieters, A, Wang, Z et al.. Correction: Distinct germline genetic susceptibility profiles identified for common non-Hodgkin lymphoma subtypes. Leukemia. 2023;37 (10):2142. doi: 10.1038/s41375-023-01978-x. PubMed PMID:37666943 .
  59. Bouras, E, Kim, AE, Lin, Y, Morrison, J, Du, M, Albanes, D et al.. Genome-wide interaction analysis of folate for colorectal cancer risk. Am J Clin Nutr. 2023;118 (5):881-891. doi: 10.1016/j.ajcnut.2023.08.010. PubMed PMID:37640106 PubMed Central PMC10636229.
  60. Kachuri, L, Chatterjee, N, Hirbo, J, Schaid, DJ, Martin, I, Kullo, IJ et al.. Principles and methods for transferring polygenic risk scores across global populations. Nat Rev Genet. 2024;25 (1):8-25. doi: 10.1038/s41576-023-00637-2. PubMed PMID:37620596 PubMed Central PMC10961971.
  61. Ito, S, Liu, X, Ishikawa, Y, Conti, DD, Otomo, N, Kote-Jarai, Z et al.. Androgen receptor binding sites enabling genetic prediction of mortality due to prostate cancer in cancer-free subjects. Nat Commun. 2023;14 (1):4863. doi: 10.1038/s41467-023-39858-8. PubMed PMID:37612283 PubMed Central PMC10447511.
  62. Mahmood, K, Thomas, M, Qu, C, Gecco-Ccfr Consortium, Hsu, L, Buchanan, DD et al.. Elucidating the Risk of Colorectal Cancer for Variants in Hereditary Colorectal Cancer Genes. Gastroenterology. 2023;165 (4):1070-1076.e3. doi: 10.1053/j.gastro.2023.06.032. PubMed PMID:37453563 PubMed Central PMC10866455.
  63. Dimou, N, Kim, AE, Flanagan, O, Murphy, N, Diez-Obrero, V, Shcherbina, A et al.. Probing the diabetes and colorectal cancer relationship using gene - environment interaction analyses. Br J Cancer. 2023;129 (3):511-520. doi: 10.1038/s41416-023-02312-z. PubMed PMID:37365285 PubMed Central PMC10403521.
  64. Darst, BF, Shen, J, Madduri, RK, Rodriguez, AA, Xiao, Y, Sheng, X et al.. Evaluating approaches for constructing polygenic risk scores for prostate cancer in men of African and European ancestry. Am J Hum Genet. 2023;110 (7):1200-1206. doi: 10.1016/j.ajhg.2023.05.010. PubMed PMID:37311464 PubMed Central PMC10357473.
  65. Darst, BF, Shen, J, Madduri, RK, Rodriguez, AA, Xiao, Y, Sheng, X et al.. Evaluating Approaches for Constructing Polygenic Risk Scores for Prostate Cancer in Men of African and European Ancestry. medRxiv. 2023; :. doi: 10.1101/2023.05.12.23289860. PubMed PMID:37292833 PubMed Central PMC10246022.
  66. Kachuri, L, Hoffmann, TJ, Jiang, Y, Berndt, SI, Shelley, JP, Schaffer, KR et al.. Genetically adjusted PSA levels for prostate cancer screening. Nat Med. 2023;29 (6):1412-1423. doi: 10.1038/s41591-023-02277-9. PubMed PMID:37264206 PubMed Central PMC10287565.
  67. Aglago, EK, Kim, A, Lin, Y, Qu, C, Evangelou, M, Ren, Y et al.. A Genetic Locus within the FMN1/GREM1 Gene Region Interacts with Body Mass Index in Colorectal Cancer Risk. Cancer Res. 2023;83 (15):2572-2583. doi: 10.1158/0008-5472.CAN-22-3713. PubMed PMID:37249599 PubMed Central PMC10391330.
  68. Chen, DM, Dong, R, Kachuri, L, Hoffmann, T, Jiang, Y, Berndt, SI et al.. Transcriptome-Wide Association Analysis Identifies Novel Candidate Susceptibility Genes for Prostate-Specific Antigen Levels in Men Without Prostate Cancer. medRxiv. 2023; :. doi: 10.1101/2023.05.04.23289526. PubMed PMID:37205487 PubMed Central PMC10187439.
  69. Yarmolinsky, J, Bouras, E, Constantinescu, A, Burrows, K, Bull, CJ, Vincent, EE et al.. Genetically proxied glucose-lowering drug target perturbation and risk of cancer: a Mendelian randomisation analysis. Diabetologia. 2023;66 (8):1481-1500. doi: 10.1007/s00125-023-05925-4. PubMed PMID:37171501 PubMed Central PMC10317892.
  70. Pernet, O, Weisenhaus, M, Stafylis, C, Williams, C, Campan, M, Pettersson, J et al.. SARS-CoV-2 viral variants can rapidly be identified for clinical decision making and population surveillance using a high-throughput digital droplet PCR assay. Sci Rep. 2023;13 (1):7612. doi: 10.1038/s41598-023-34188-7. PubMed PMID:37165019 PubMed Central PMC10170421.
  71. Chan, TF, Rui, X, Conti, DV, Fornage, M, Graff, M, Haessler, J et al.. Estimating heritability explained by local ancestry and evaluating stratification bias in admixture mapping from summary statistics. bioRxiv. 2023; :. doi: 10.1101/2023.04.10.536252. PubMed PMID:37131817 PubMed Central PMC10153181.
  72. Stafylis, C, Pernet, O, Hernandez-Tamayo, C, Kovacs, A, Emerson, J, Ward, PM et al.. Surveillance of Severe Acute Respiratory Syndrome Coronavirus 2 and Variants Using Digital Droplet Polymerase Chain Reaction at a Large University and Healthcare System in California. Open Forum Infect Dis. 2023;10 (4):ofad147. doi: 10.1093/ofid/ofad147. PubMed PMID:37089777 PubMed Central PMC10117372.
  73. Hou, K, Ding, Y, Xu, Z, Wu, Y, Bhattacharya, A, Mester, R et al.. Causal effects on complex traits are similar for common variants across segments of different continental ancestries within admixed individuals. Nat Genet. 2023;55 (4):549-558. doi: 10.1038/s41588-023-01338-6. PubMed PMID:36941441 PubMed Central PMC11120833.
  74. Chen, F, Madduri, RK, Rodriguez, AA, Darst, BF, Chou, A, Sheng, X et al.. Evidence of Novel Susceptibility Variants for Prostate Cancer and a Multiancestry Polygenic Risk Score Associated with Aggressive Disease in Men of African Ancestry. Eur Urol. 2023;84 (1):13-21. doi: 10.1016/j.eururo.2023.01.022. PubMed PMID:36872133 PubMed Central PMC10424812.
  75. Rahman, MM, Lorenzo, M, Ban-Weiss, G, Hasan, Z, Azzouz, M, Eckel, SP et al.. Ambient temperature and air pollution associations with suicide and homicide mortality in California: A statewide case-crossover study. Sci Total Environ. 2023;874 :162462. doi: 10.1016/j.scitotenv.2023.162462. PubMed PMID:36858215 PubMed Central PMC10465171.
  76. Goodrich, JA, Walker, DI, He, J, Lin, X, Baumert, BO, Hu, X et al.. Metabolic Signatures of Youth Exposure to Mixtures of Per- and Polyfluoroalkyl Substances: A Multi-Cohort Study. Environ Health Perspect. 2023;131 (2):27005. doi: 10.1289/EHP11372. PubMed PMID:36821578 PubMed Central PMC9945578.
  77. Thomas, M, Su, YR, Rosenthal, EA, Sakoda, LC, Schmit, SL, Timofeeva, MN et al.. Combining Asian-European Genome-Wide Association Studies of Colorectal Cancer Improves Risk Prediction Across Race and Ethnicity. medRxiv. 2023; :. doi: 10.1101/2023.01.19.23284737. PubMed PMID:36789420 PubMed Central PMC9928144.
  78. Fernandez-Rozadilla, C, Timofeeva, M, Chen, Z, Law, P, Thomas, M, Schmit, S et al.. Author Correction: Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries. Nat Genet. 2023;55 (3):519-520. doi: 10.1038/s41588-023-01334-w. PubMed PMID:36782065 .
  79. Larionov, A, Fewings, E, Redman, J, Goldgraben, M, Clark, G, Boice, J et al.. The Contribution of Germline Pathogenic Variants in Breast Cancer Genes to Contralateral Breast Cancer Risk in BRCA1/BRCA2/PALB2-Negative Women. Cancers (Basel). 2023;15 (2):. doi: 10.3390/cancers15020415. PubMed PMID:36672364 PubMed Central PMC9856968.
  80. Haiman, CA, Kote-Jarai, Z, Darst, BF, Conti, DV. RE: Polygenic risk of any, metastatic, and fatal prostate cancer in the Million Veteran Program. J Natl Cancer Inst. 2023;115 (3):341-342. doi: 10.1093/jnci/djad005. PubMed PMID:36629487 PubMed Central PMC9996202.
  81. Nicolo, M, Kawaguchi, E, Ghanem-Uzqueda, A, Kim, AE, Soto, D, Deva, S et al.. Correlates of COVID-19 vaccination status among college students. J Am Coll Health. 2024;72 (9):3136-3138. doi: 10.1080/07448481.2022.2157216. PubMed PMID:36596228 PubMed Central PMC10315412.
  82. Carreras-Torres, R, Kim, AE, Lin, Y, Díez-Obrero, V, Bien, SA, Qu, C et al.. Genome-wide Interaction Study with Smoking for Colorectal Cancer Risk Identifies Novel Genetic Loci Related to Tumor Suppression, Inflammation, and Immune Response. Cancer Epidemiol Biomarkers Prev. 2023;32 (3):315-328. doi: 10.1158/1055-9965.EPI-22-0763. PubMed PMID:36576985 PubMed Central PMC9992283.
  83. Fernandez-Rozadilla, C, Timofeeva, M, Chen, Z, Law, P, Thomas, M, Schmit, S et al.. Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries. Nat Genet. 2023;55 (1):89-99. doi: 10.1038/s41588-022-01222-9. PubMed PMID:36539618 PubMed Central PMC10094749.
  84. Sheng, X, Xia, L, Cahoon, JL, Conti, DV, Haiman, CA, Kachuri, L et al.. Inverted genomic regions between reference genome builds in humans impact imputation accuracy and decrease the power of association testing. HGG Adv. 2023;4 (1):100159. doi: 10.1016/j.xhgg.2022.100159. PubMed PMID:36465187 PubMed Central PMC9709082.
  85. Haas, CB, Su, YR, Petersen, P, Wang, X, Bien, SA, Lin, Y et al.. Interactions between folate intake and genetic predictors of gene expression levels associated with colorectal cancer risk. Sci Rep. 2022;12 (1):18852. doi: 10.1038/s41598-022-23451-y. PubMed PMID:36344807 PubMed Central PMC9640550.
  86. Berndt, SI, Vijai, J, Benavente, Y, Camp, NJ, Nieters, A, Wang, Z et al.. Distinct germline genetic susceptibility profiles identified for common non-Hodgkin lymphoma subtypes. Leukemia. 2022;36 (12):2835-2844. doi: 10.1038/s41375-022-01711-0. PubMed PMID:36273105 PubMed Central PMC10337695.
  87. Fernández-Rhodes, L, Graff, M, Buchanan, VL, Justice, AE, Highland, HM, Guo, X et al.. Erratum: Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits-The Hispanic/Latino Anthropometry Consortium. HGG Adv. 2023;4 (1):100149. doi: 10.1016/j.xhgg.2022.100149. PubMed PMID:36268164 PubMed Central PMC9576563.
  88. Costello, E, Goodrich, J, Patterson, WB, Rock, S, Li, Y, Baumert, B et al.. Diet Quality Is Associated with Glucose Regulation in a Cohort of Young Adults. Nutrients. 2022;14 (18):. doi: 10.3390/nu14183734. PubMed PMID:36145110 PubMed Central PMC9501084.
  89. Chou, A, Darst, BF, Wilkens, LR, Marchand, LL, Lilja, H, Conti, DV et al.. Association of Prostate-Specific Antigen Levels with Prostate Cancer Risk in a Multiethnic Population: Stability Over Time and Comparison with Polygenic Risk Score. Cancer Epidemiol Biomarkers Prev. 2022;31 (12):2199-2207. doi: 10.1158/1055-9965.EPI-22-0443. PubMed PMID:36126957 PubMed Central PMC9729398.
  90. Goodrich, JA, Walker, D, Lin, X, Wang, H, Lim, T, McConnell, R et al.. Exposure to perfluoroalkyl substances and risk of hepatocellular carcinoma in a multiethnic cohort. JHEP Rep. 2022;4 (10):100550. doi: 10.1016/j.jhepr.2022.100550. PubMed PMID:36111068 PubMed Central PMC9468464.
  91. Kim, MS, Naidoo, D, Hazra, U, Quiver, MH, Chen, WC, Simonti, CN et al.. Testing the generalizability of ancestry-specific polygenic risk scores to predict prostate cancer in sub-Saharan Africa. Genome Biol. 2022;23 (1):194. doi: 10.1186/s13059-022-02766-z. PubMed PMID:36100952 PubMed Central PMC9472407.
  92. Wang, A, Xu, Y, Yu, Y, Nead, KT, Kim, T, Xu, K et al.. Clonal hematopoiesis and risk of prostate cancer in large samples of European ancestry men. Hum Mol Genet. 2023;32 (3):489-495. doi: 10.1093/hmg/ddac214. PubMed PMID:36018819 PubMed Central PMC9851740.
  93. Lu, Z, Gopalan, S, Yuan, D, Conti, DV, Pasaniuc, B, Gusev, A et al.. Multi-ancestry fine-mapping improves precision to identify causal genes in transcriptome-wide association studies. Am J Hum Genet. 2022;109 (8):1388-1404. doi: 10.1016/j.ajhg.2022.07.002. PubMed PMID:35931050 PubMed Central PMC9388396.
  94. Chen, F, Park, SL, Wilkens, LR, Wan, P, Hart, SN, Hu, C et al.. Genetic Risk of Second Primary Cancer in Breast Cancer Survivors: The Multiethnic Cohort Study. Cancer Res. 2022;82 (18):3201-3208. doi: 10.1158/0008-5472.CAN-21-4461. PubMed PMID:35834270 PubMed Central PMC9481694.
  95. Chen, F, Darst, BF, Madduri, RK, Rodriguez, AA, Sheng, X, Rentsch, CT et al.. Validation of a multi-ancestry polygenic risk score and age-specific risks of prostate cancer: A meta-analysis within diverse populations. Elife. 2022;11 :. doi: 10.7554/eLife.78304. PubMed PMID:35801699 PubMed Central PMC9322982.
  96. Midya, V, Colicino, E, Conti, DV, Berhane, K, Garcia, E, Stratakis, N et al.. Association of Prenatal Exposure to Endocrine-Disrupting Chemicals With Liver Injury in Children. JAMA Netw Open. 2022;5 (7):e2220176. doi: 10.1001/jamanetworkopen.2022.20176. PubMed PMID:35793087 PubMed Central PMC9260485.
  97. Watts, EL, Perez-Cornago, A, Fensom, GK, Smith-Byrne, K, Noor, U, Andrews, CD et al.. Circulating insulin-like growth factors and risks of overall, aggressive and early-onset prostate cancer: a collaborative analysis of 20 prospective studies and Mendelian randomization analysis. Int J Epidemiol. 2023;52 (1):71-86. doi: 10.1093/ije/dyac124. PubMed PMID:35726641 PubMed Central PMC9908067.
  98. Colicino, E, Margetaki, K, Valvi, D, Pedretti, NF, Stratakis, N, Vafeiadi, M et al.. Prenatal exposure to multiple organochlorine compounds and childhood body mass index. Environ Epidemiol. 2022;6 (3):e201. doi: 10.1097/EE9.0000000000000201. PubMed PMID:35702503 PubMed Central PMC9187184.
  99. Gao, G, Zhao, F, Ahearn, TU, Lunetta, KL, Troester, MA, Du, Z et al.. Polygenic risk scores for prediction of breast cancer risk in women of African ancestry: a cross-ancestry approach. Hum Mol Genet. 2022;31 (18):3133-3143. doi: 10.1093/hmg/ddac102. PubMed PMID:35554533 PubMed Central PMC9476624.
  100. Tian, Y, Kim, AE, Bien, SA, Lin, Y, Qu, C, Harrison, TA et al.. Genome-Wide Interaction Analysis of Genetic Variants With Menopausal Hormone Therapy for Colorectal Cancer Risk. J Natl Cancer Inst. 2022;114 (8):1135-1148. doi: 10.1093/jnci/djac094. PubMed PMID:35512400 PubMed Central PMC9360460.
  101. Nicolo, M, Kawaguchi, ES, Ghanem-Uzqueda, A, Kim, AE, Soto, D, Deva, S et al.. Characteristics associated with COVID-19 vaccination status among staff and faculty of a large, diverse University in Los Angeles: The Trojan Pandemic Response Initiative. Prev Med Rep. 2022;27 :101802. doi: 10.1016/j.pmedr.2022.101802. PubMed PMID:35493961 PubMed Central PMC9034831.
  102. Costello, E, Rock, S, Stratakis, N, Eckel, SP, Walker, DI, Valvi, D et al.. Exposure to per- and Polyfluoroalkyl Substances and Markers of Liver Injury: A Systematic Review and Meta-Analysis. Environ Health Perspect. 2022;130 (4):46001. doi: 10.1289/EHP10092. PubMed PMID:35475652 PubMed Central PMC9044977.
  103. Baumert, BO, Goodrich, JA, Hu, X, Walker, DI, Alderete, TL, Chen, Z et al.. Plasma concentrations of lipophilic persistent organic pollutants and glucose homeostasis in youth populations. Environ Res. 2022;212 (Pt B):113296. doi: 10.1016/j.envres.2022.113296. PubMed PMID:35447156 PubMed Central PMC9831292.
  104. Jordahl, KM, Shcherbina, A, Kim, AE, Su, YR, Lin, Y, Wang, J et al.. Beyond GWAS of Colorectal Cancer: Evidence of Interaction with Alcohol Consumption and Putative Causal Variant for the 10q24.2 Region. Cancer Epidemiol Biomarkers Prev. 2022;31 (5):1077-1089. doi: 10.1158/1055-9965.EPI-21-1003. PubMed PMID:35438744 PubMed Central PMC9081195.
  105. Mohajerani, A, Kurmus, H, Conti, D, Cash, L, Semcesen, A, Abdurahman, M et al.. Environmental impacts and leachate analysis of waste rubber incorporated in construction and road materials: A review. Sci Total Environ. 2022;835 :155269. doi: 10.1016/j.scitotenv.2022.155269. PubMed PMID:35430184 .
  106. Fernández-Rhodes, L, Graff, M, Buchanan, VL, Justice, AE, Highland, HM, Guo, X et al.. Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits-The Hispanic/Latino Anthropometry Consortium. HGG Adv. 2022;3 (2):100099. doi: 10.1016/j.xhgg.2022.100099. PubMed PMID:35399580 PubMed Central PMC8990175.
  107. Morales Berstein, F, McCartney, DL, Lu, AT, Tsilidis, KK, Bouras, E, Haycock, P et al.. Assessing the causal role of epigenetic clocks in the development of multiple cancers: a Mendelian randomization study. Elife. 2022;11 :. doi: 10.7554/eLife.75374. PubMed PMID:35346416 PubMed Central PMC9049976.
  108. Stratakis, N, Siskos, AP, Papadopoulou, E, Nguyen, AN, Zhao, Y, Margetaki, K et al.. Urinary metabolic biomarkers of diet quality in European children are associated with metabolic health. Elife. 2022;11 :. doi: 10.7554/eLife.71332. PubMed PMID:35076016 PubMed Central PMC8789316.
  109. Darst, BF, Hughley, R, Pfennig, A, Hazra, U, Fan, C, Wan, P et al.. A Rare Germline HOXB13 Variant Contributes to Risk of Prostate Cancer in Men of African Ancestry. Eur Urol. 2022;81 (5):458-462. doi: 10.1016/j.eururo.2021.12.023. PubMed PMID:35031163 PubMed Central PMC9018520.
  110. Vrijheid, M, Basagaña, X, Gonzalez, JR, Jaddoe, VWV, Jensen, G, Keun, HC et al.. Advancing tools for human early lifecourse exposome research and translation (ATHLETE): Project overview. Environ Epidemiol. 2021;5 (5):e166. doi: 10.1097/EE9.0000000000000166. PubMed PMID:34934888 PubMed Central PMC8683140.
  111. Wang, J, Conti, DV, Epeldegui, M, Ollikainen, M, Tyndale, RF, Hwang, AE et al.. Lymphoma-Associated Biomarkers Are Increased in Current Smokers in Twin Pairs Discordant for Smoking. Cancers (Basel). 2021;13 (21):. doi: 10.3390/cancers13215395. PubMed PMID:34771561 PubMed Central PMC8582438.
  112. Stratakis, N, Rock, S, La Merrill, MA, Saez, M, Robinson, O, Fecht, D et al.. Prenatal exposure to persistent organic pollutants and childhood obesity: A systematic review and meta-analysis of human studies. Obes Rev. 2022;23 Suppl 1 (Suppl 1):e13383. doi: 10.1111/obr.13383. PubMed PMID:34766696 PubMed Central PMC9512275.
  113. Wang, J, Conti, DV, Bogumil, D, Sheng, X, Noureddin, M, Wilkens, LR et al.. Association of Genetic Risk Score With NAFLD in An Ethnically Diverse Cohort. Hepatol Commun. 2021;5 (10):1689-1703. doi: 10.1002/hep4.1751. PubMed PMID:34558842 PubMed Central PMC8485887.
  114. Wu, C, Zhu, J, King, A, Tong, X, Lu, Q, Park, JY et al.. Novel strategy for disease risk prediction incorporating predicted gene expression and DNA methylation data: a multi-phased study of prostate cancer. Cancer Commun (Lond). 2021;41 (12):1387-1397. doi: 10.1002/cac2.12205. PubMed PMID:34520132 PubMed Central PMC8696216.
  115. Papadopoulou, E, Stratakis, N, Basagaña, X, Brantsæter, AL, Casas, M, Fossati, S et al.. Prenatal and postnatal exposure to PFAS and cardiometabolic factors and inflammation status in children from six European cohorts. Environ Int. 2021;157 :106853. doi: 10.1016/j.envint.2021.106853. PubMed PMID:34500361 .
  116. Goodrich, JA, Alderete, TL, Baumert, BO, Berhane, K, Chen, Z, Gilliland, FD et al.. Exposure to Perfluoroalkyl Substances and Glucose Homeostasis in Youth. Environ Health Perspect. 2021;129 (9):97002. doi: 10.1289/EHP9200. PubMed PMID:34468161 PubMed Central PMC8409228.
  117. Hainley, LE, Hughson, MS, Narendran, A, Smith, R, Arthur, J, Hayner-Buchan, A et al.. Chk1 and the Host Cell DNA Damage Response as a Potential Antiviral Target in BK Polyomavirus Infection. Viruses. 2021;13 (7):. doi: 10.3390/v13071353. PubMed PMID:34372559 PubMed Central PMC8310304.
  118. Leventhal, AM, Conti, DV, Ray, LA, Baurley, JW, Bello, MS, Cho, J et al.. A genetic association study of tobacco withdrawal endophenotypes in African Americans. Exp Clin Psychopharmacol. 2022;30 (5):673-681. doi: 10.1037/pha0000492. PubMed PMID:34279980 PubMed Central PMC8928755.
  119. Higgins, CE, Tang, J, Higgins, SP, Gifford, CC, Mian, BM, Jones, DM et al.. The Genomic Response to TGF-β1 Dictates Failed Repair and Progression of Fibrotic Disease in the Obstructed Kidney. Front Cell Dev Biol. 2021;9 :678524. doi: 10.3389/fcell.2021.678524. PubMed PMID:34277620 PubMed Central PMC8284093.
  120. Adedokun, B, Du, Z, Gao, G, Ahearn, TU, Lunetta, KL, Zirpoli, G et al.. Cross-ancestry GWAS meta-analysis identifies six breast cancer loci in African and European ancestry women. Nat Commun. 2021;12 (1):4198. doi: 10.1038/s41467-021-24327-x. PubMed PMID:34234117 PubMed Central PMC8263739.
  121. Horn, AL, Jiang, L, Washburn, F, Hvitfeldt, E, de la Haye, K, Nicholas, W et al.. An integrated risk and epidemiological model to estimate risk-stratified COVID-19 outcomes for Los Angeles County: March 1, 2020-March 1, 2021. PLoS One. 2021;16 (6):e0253549. doi: 10.1371/journal.pone.0253549. PubMed PMID:34166416 PubMed Central PMC8224896.
  122. Gkatzionis, A, Burgess, S, Conti, DV, Newcombe, PJ. Bayesian variable selection with a pleiotropic loss function in Mendelian randomization. Stat Med. 2021;40 (23):5025-5045. doi: 10.1002/sim.9109. PubMed PMID:34155684 PubMed Central PMC8446304.
  123. Garcia, E, Stratakis, N, Valvi, D, Maitre, L, Varo, N, Aasvang, GM et al.. Prenatal and childhood exposure to air pollution and traffic and the risk of liver injury in European children. Environ Epidemiol. 2021;5 (3):e153. doi: 10.1097/EE9.0000000000000153. PubMed PMID:34131614 PubMed Central PMC8196121.
  124. Auslander, A, McKean-Cowdin, R, Feigelson, D, Brindopke, F, DiBona, M, Magee, K et al.. The International Family Study of Nonsyndromic Orofacial Clefts: Design and Methods. Cleft Palate Craniofac J. 2022;59 (4_suppl2):S37-S47. doi: 10.1177/10556656211018956. PubMed PMID:34056937 .
  125. Wang, SC, Pashkovetsky, E, Conti, D, Ata, A, Torosoff, M, Fein, S et al.. Pericardial Effusion After Renal Transplantation: Timing and Clinical Characteristics. Transplant Proc. 2021;53 (5):1606-1610. doi: 10.1016/j.transproceed.2021.03.021. PubMed PMID:33966877 .
  126. Darst, BF, Sheng, X, Eeles, RA, Kote-Jarai, Z, Conti, DV, Haiman, CA et al.. Combined Effect of a Polygenic Risk Score and Rare Genetic Variants on Prostate Cancer Risk. Eur Urol. 2021;80 (2):134-138. doi: 10.1016/j.eururo.2021.04.013. PubMed PMID:33941403 PubMed Central PMC8286329.
  127. Plym, A, Penney, KL, Kalia, S, Kraft, P, Conti, DV, Haiman, C et al.. Evaluation of a Multiethnic Polygenic Risk Score Model for Prostate Cancer. J Natl Cancer Inst. 2022;114 (5):771-774. doi: 10.1093/jnci/djab058. PubMed PMID:33792693 PubMed Central PMC9086757.
  128. Du, Z, Gao, G, Adedokun, B, Ahearn, T, Lunetta, KL, Zirpoli, G et al.. Evaluating Polygenic Risk Scores for Breast Cancer in Women of African Ancestry. J Natl Cancer Inst. 2021;113 (9):1168-1176. doi: 10.1093/jnci/djab050. PubMed PMID:33769540 PubMed Central PMC8418423.
  129. Stratakis, N, Golden-Mason, L, Margetaki, K, Zhao, Y, Valvi, D, Garcia, E et al.. In Utero Exposure to Mercury Is Associated With Increased Susceptibility to Liver Injury and Inflammation in Childhood. Hepatology. 2021;74 (3):1546-1559. doi: 10.1002/hep.31809. PubMed PMID:33730435 PubMed Central PMC8446089.
  130. Graff, M, Justice, AE, Young, KL, Marouli, E, Zhang, X, Fine, RS et al.. Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry. Am J Hum Genet. 2021;108 (4):564-582. doi: 10.1016/j.ajhg.2021.02.011. PubMed PMID:33713608 PubMed Central PMC8059339.
  131. Huyghe, JR, Harrison, TA, Bien, SA, Hampel, H, Figueiredo, JC, Schmit, SL et al.. Genetic architectures of proximal and distal colorectal cancer are partly distinct. Gut. 2021;70 (7):1325-1334. doi: 10.1136/gutjnl-2020-321534. PubMed PMID:33632709 PubMed Central PMC8223655.
  132. Matejcic, M, Shaban, HA, Quintana, MW, Schumacher, FR, Edlund, CK, Naghi, L et al.. Rare Variants in the DNA Repair Pathway and the Risk of Colorectal Cancer. Cancer Epidemiol Biomarkers Prev. 2021;30 (5):895-903. doi: 10.1158/1055-9965.EPI-20-1457. PubMed PMID:33627384 PubMed Central PMC8102340.
  133. Burton, CL, Lemire, M, Xiao, B, Corfield, EC, Erdman, L, Bralten, J et al.. Genome-wide association study of pediatric obsessive-compulsive traits: shared genetic risk between traits and disorder. Transl Psychiatry. 2021;11 (1):91. doi: 10.1038/s41398-020-01121-9. PubMed PMID:33531474 PubMed Central PMC7870035.
  134. Conti, DV, Darst, BF, Moss, LC, Saunders, EJ, Sheng, X, Chou, A et al.. Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction. Nat Genet. 2021;53 (3):413. doi: 10.1038/s41588-021-00786-2. PubMed PMID:33473200 .
  135. Howe, CG, Margetaki, K, Vafeiadi, M, Roumeliotaki, T, Karachaliou, M, Kogevinas, M et al.. Prenatal metal mixtures and child blood pressure in the Rhea mother-child cohort in Greece. Environ Health. 2021;20 (1):1. doi: 10.1186/s12940-020-00685-9. PubMed PMID:33407552 PubMed Central PMC7789252.
  136. Jiang, L, Xu, S, Mancuso, N, Newcombe, PJ, Conti, DV. A Hierarchical Approach Using Marginal Summary Statistics for Multiple Intermediates in a Mendelian Randomization or Transcriptome Analysis. Am J Epidemiol. 2021;190 (6):1148-1158. doi: 10.1093/aje/kwaa287. PubMed PMID:33404048 PubMed Central PMC8521785.
  137. Conti, DV, Darst, BF, Moss, LC, Saunders, EJ, Sheng, X, Chou, A et al.. Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction. Nat Genet. 2021;53 (1):65-75. doi: 10.1038/s41588-020-00748-0. PubMed PMID:33398198 PubMed Central PMC8148035.
  138. Kawaguchi, ES, Darst, BF, Wang, K, Conti, DV. Sign-based Shrinkage Based on an Asymmetric LASSO Penalty. J Data Sci. 2021;19 (3):429-449. doi: 10.6339/21-JDS1015. PubMed PMID:35222618 PubMed Central PMC8880910.
  139. Horn, AL, Jiang, L, Washburn, F, Hvitfeldt, E, de la Haye, K, Nicholas, W et al.. Estimation of COVID-19 risk-stratified epidemiological parameters and policy implications for Los Angeles County through an integrated risk and stochastic epidemiological model. medRxiv. 2020; :. doi: 10.1101/2020.12.11.20209627. PubMed PMID:33367291 PubMed Central PMC7756248.
  140. Auslander, A, McKean-Cowdin, R, Brindopke, F, Sylvester, B, DiBona, M, Magee, K et al.. The role of smoke from cooking indoors over an open flame and parental smoking on the risk of cleft lip and palate: A case- control study in 7 low-resource countries. J Glob Health. 2020;10 (2):020410. doi: 10.7189/jogh.10.020410. PubMed PMID:33110573 PubMed Central PMC7568926.
  141. Tilley, K, Ayvazyan, V, Martinez, L, Nanda, N, Kawaguchi, ES, O'Gorman, M et al.. A Cross-Sectional Study Examining the Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus 2 Antibodies in a University Student Population. J Adolesc Health. 2020;67 (6):763-768. doi: 10.1016/j.jadohealth.2020.09.001. PubMed PMID:33071164 PubMed Central PMC7557277.
  142. Guo, X, Lin, W, Wen, W, Huyghe, J, Bien, S, Cai, Q et al.. Identifying Novel Susceptibility Genes for Colorectal Cancer Risk From a Transcriptome-Wide Association Study of 125,478 Subjects. Gastroenterology. 2021;160 (4):1164-1178.e6. doi: 10.1053/j.gastro.2020.08.062. PubMed PMID:33058866 PubMed Central PMC7956223.
  143. Bogumil, D, Conti, DV, Sheng, X, Xia, L, Shu, XO, Pandol, SJ et al.. Replication and Genetic Risk Score Analysis for Pancreatic Cancer in a Diverse Multiethnic Population. Cancer Epidemiol Biomarkers Prev. 2020;29 (12):2686-2692. doi: 10.1158/1055-9965.EPI-20-0963. PubMed PMID:32958499 PubMed Central PMC7710597.
  144. Chen, Z, Yang, T, Walker, DI, Thomas, DC, Qiu, C, Chatzi, L et al.. Dysregulated lipid and fatty acid metabolism link perfluoroalkyl substances exposure and impaired glucose metabolism in young adults. Environ Int. 2020;145 :106091. doi: 10.1016/j.envint.2020.106091. PubMed PMID:32892005 PubMed Central PMC8009052.
  145. Darst, BF, Dadaev, T, Saunders, E, Sheng, X, Wan, P, Pooler, L et al.. Germline Sequencing DNA Repair Genes in 5545 Men With Aggressive and Nonaggressive Prostate Cancer. J Natl Cancer Inst. 2021;113 (5):616-625. doi: 10.1093/jnci/djaa132. PubMed PMID:32853339 PubMed Central PMC8599772.
  146. Matejcic, M, Patel, Y, Lilyquist, J, Hu, C, Lee, KY, Gnanaolivu, RD et al.. Pathogenic Variants in Cancer Predisposition Genes and Prostate Cancer Risk in Men of African Ancestry. JCO Precis Oncol. 2020;4 :32-43. doi: 10.1200/po.19.00179. PubMed PMID:32832836 PubMed Central PMC7442213.
  147. Croasdale, DR, Garner, MS, Ashar, A, Paul Singh, T, Tafen-Wandji, M, Stain, SC et al.. Concomitant Abdominal Hernia Repair and Peritoneal Dialysis Catheter Insertion: A Retrospective Analysis. Am Surg. 2021;87 (12):2000-2002. doi: 10.1177/0003134820940269. PubMed PMID:32829646 .
  148. Wu, L, Yang, Y, Guo, X, Shu, XO, Cai, Q, Shu, X et al.. An integrative multi-omics analysis to identify candidate DNA methylation biomarkers related to prostate cancer risk. Nat Commun. 2020;11 (1):3905. doi: 10.1038/s41467-020-17673-9. PubMed PMID:32764609 PubMed Central PMC7413371.
  149. Valvi, D, Walker, DI, Inge, T, Bartell, SM, Jenkins, T, Helmrath, M et al.. Environmental chemical burden in metabolic tissues and systemic biological pathways in adolescent bariatric surgery patients: A pilot untargeted metabolomic approach. Environ Int. 2020;143 :105957. doi: 10.1016/j.envint.2020.105957. PubMed PMID:32683211 PubMed Central PMC7708399.
  150. Yu, Y, Brown Wade, N, Hwang, AE, Nooka, AK, Fiala, MA, Mohrbacher, A et al.. Variability in Cytogenetic Testing for Multiple Myeloma: A Comprehensive Analysis From Across the United States. JCO Oncol Pract. 2020;16 (10):e1169-e1180. doi: 10.1200/JOP.19.00639. PubMed PMID:32469686 PubMed Central PMC7564132.
  151. Darst, BF, Wan, P, Sheng, X, Bensen, JT, Ingles, SA, Rybicki, BA et al.. A Germline Variant at 8q24 Contributes to Familial Clustering of Prostate Cancer in Men of African Ancestry. Eur Urol. 2020;78 (3):316-320. doi: 10.1016/j.eururo.2020.04.060. PubMed PMID:32409115 PubMed Central PMC7805560.
  152. Darst, BF, Chou, A, Wan, P, Pooler, L, Sheng, X, Vertosick, EA et al.. The Four-Kallikrein Panel Is Effective in Identifying Aggressive Prostate Cancer in a Multiethnic Population. Cancer Epidemiol Biomarkers Prev. 2020;29 (7):1381-1388. doi: 10.1158/1055-9965.EPI-19-1560. PubMed PMID:32385116 PubMed Central PMC7334056.
  153. Wadé, NB, Chang, CM, Conti, D, Millstein, J, Skibola, C, Nieters, A et al.. Correction to: Infectious mononucleosis, immune genotypes, and non-Hodgkin lymphoma (NHL): an InterLymph Consortium study. Cancer Causes Control. 2020;31 (6):607. doi: 10.1007/s10552-020-01297-x. PubMed PMID:32227299 .
  154. Hollis, B, Day, FR, Busch, AS, Thompson, DJ, Soares, ALG, Timmers, PRHJ et al.. Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan. Nat Commun. 2020;11 (1):1536. doi: 10.1038/s41467-020-14451-5. PubMed PMID:32210231 PubMed Central PMC7093467.
  155. Xia, Z, Su, YR, Petersen, P, Qi, L, Kim, AE, Figueiredo, JC et al.. Functional informed genome-wide interaction analysis of body mass index, diabetes and colorectal cancer risk. Cancer Med. 2020;9 (10):3563-3573. doi: 10.1002/cam4.2971. PubMed PMID:32207560 PubMed Central PMC7221445.
  156. Stratakis, N, Conti, DV, Borras, E, Sabido, E, Roumeliotaki, T, Papadopoulou, E et al.. Association of Fish Consumption and Mercury Exposure During Pregnancy With Metabolic Health and Inflammatory Biomarkers in Children. JAMA Netw Open. 2020;3 (3):e201007. doi: 10.1001/jamanetworkopen.2020.1007. PubMed PMID:32176304 PubMed Central PMC7076335.
  157. Wadé, NB, Chang, CM, Conti, D, Millstein, J, Skibola, C, Nieters, A et al.. Infectious mononucleosis, immune genotypes, and non-Hodgkin lymphoma (NHL): an InterLymph Consortium study. Cancer Causes Control. 2020;31 (5):451-462. doi: 10.1007/s10552-020-01266-4. PubMed PMID:32124188 PubMed Central PMC7534692.
  158. Khankari, NK, Banbury, BL, Borges, MC, Haycock, P, Albanes, D, Arndt, V et al.. Mendelian Randomization of Circulating Polyunsaturated Fatty Acids and Colorectal Cancer Risk. Cancer Epidemiol Biomarkers Prev. 2020;29 (4):860-870. doi: 10.1158/1055-9965.EPI-19-0891. PubMed PMID:32051193 PubMed Central PMC7125012.
  159. Epeldegui, M, Conti, DV, Guo, Y, Cozen, W, Penichet, ML, Martínez-Maza, O et al.. Author Correction: Elevated numbers of PD-L1 expressing B cells are associated with the development of AIDS-NHL. Sci Rep. 2020;10 (1):748. doi: 10.1038/s41598-020-57442-8. PubMed PMID:31937870 PubMed Central PMC6960160.
  160. Du, Z, Weinhold, N, Song, GC, Rand, KA, Van Den Berg, DJ, Hwang, AE et al.. A meta-analysis of genome-wide association studies of multiple myeloma among men and women of African ancestry. Blood Adv. 2020;4 (1):181-190. doi: 10.1182/bloodadvances.2019000491. PubMed PMID:31935283 PubMed Central PMC6960456.
  161. Archambault, AN, Su, YR, Jeon, J, Thomas, M, Lin, Y, Conti, DV et al.. Cumulative Burden of Colorectal Cancer-Associated Genetic Variants Is More Strongly Associated With Early-Onset vs Late-Onset Cancer. Gastroenterology. 2020;158 (5):1274-1286.e12. doi: 10.1053/j.gastro.2019.12.012. PubMed PMID:31866242 PubMed Central PMC7103489.
  162. Jin, R, McConnell, R, Catherine, C, Xu, S, Walker, DI, Stratakis, N et al.. Perfluoroalkyl substances and severity of nonalcoholic fatty liver in Children: An untargeted metabolomics approach. Environ Int. 2020;134 :105220. doi: 10.1016/j.envint.2019.105220. PubMed PMID:31744629 PubMed Central PMC6944061.
  163. Matloff, WJ, Zhao, L, Ning, K, Conti, DV, Toga, AW. Interaction effect of alcohol consumption and Alzheimer disease polygenic risk score on the brain cortical thickness of cognitively normal subjects. Alcohol. 2020;85 :1-12. doi: 10.1016/j.alcohol.2019.11.002. PubMed PMID:31734309 PubMed Central PMC7220836.
  164. Watt, GP, Reiner, AS, Smith, SA, Stram, DO, Capanu, M, Malone, KE et al.. Association of a Pathway-Specific Genetic Risk Score With Risk of Radiation-Associated Contralateral Breast Cancer. JAMA Netw Open. 2019;2 (9):e1912259. doi: 10.1001/jamanetworkopen.2019.12259. PubMed PMID:31560388 PubMed Central PMC6777239.
  165. Jiang, X, Finucane, HK, Schumacher, FR, Schmit, SL, Tyrer, JP, Han, Y et al.. Publisher Correction: Shared heritability and functional enrichment across six solid cancers. Nat Commun. 2019;10 (1):4386. doi: 10.1038/s41467-019-12095-8. PubMed PMID:31548585 PubMed Central PMC6757065.
  166. Yang, Z, Pandey, P, Shibata, D, Conti, DV, Marjoram, P, Siegmund, KD et al.. HiLDA: a statistical approach to investigate differences in mutational signatures. PeerJ. 2019;7 :e7557. doi: 10.7717/peerj.7557. PubMed PMID:31523512 PubMed Central PMC6717498.
  167. Peng, C, Wang, J, Asante, I, Louie, S, Jin, R, Chatzi, L et al.. A latent unknown clustering integrating multi-omics data (LUCID) with phenotypic traits. Bioinformatics. 2020;36 (3):842-850. doi: 10.1093/bioinformatics/btz667. PubMed PMID:31504184 PubMed Central PMC7986585.
  168. Wang, J, Asante, I, Baron, JA, Figueiredo, JC, Haile, R, Joan Levine, A et al.. Genome-wide association study of circulating folate one-carbon metabolites. Genet Epidemiol. 2019;43 (8):1030-1045. doi: 10.1002/gepi.22249. PubMed PMID:31502714 PubMed Central PMC6829035.
  169. Din, L, Sheikh, M, Kosaraju, N, Smedby, KE, Bernatsky, S, Berndt, SI et al.. Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes. Genet Epidemiol. 2019;43 (7):844-863. doi: 10.1002/gepi.22242. PubMed PMID:31407831 PubMed Central PMC6763347.
  170. Higgins, CE, Tang, J, Mian, BM, Higgins, SP, Gifford, CC, Conti, DJ et al.. TGF-β1-p53 cooperativity regulates a profibrotic genomic program in the kidney: molecular mechanisms and clinical implications. FASEB J. 2019;33 (10):10596-10606. doi: 10.1096/fj.201900943R. PubMed PMID:31284746 PubMed Central PMC6766640.
  171. Bien, SA, Su, YR, Conti, DV, Harrison, TA, Qu, C, Guo, X et al.. Correction to: Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer. Hum Genet. 2019;138 (7):789-791. doi: 10.1007/s00439-019-02030-8. PubMed PMID:31254090 PubMed Central PMC6828521.
  172. Epeldegui, M, Conti, DV, Guo, Y, Cozen, W, Penichet, ML, Martínez-Maza, O et al.. Elevated numbers of PD-L1 expressing B cells are associated with the development of AIDS-NHL. Sci Rep. 2019;9 (1):9371. doi: 10.1038/s41598-019-45479-3. PubMed PMID:31253857 PubMed Central PMC6599055.
  173. Ji, L, Lewinger, JP, Krailo, M, Groshen, S, Conti, DV, Asgharzadeh, S et al.. Improvements to the Escalation with Overdose Control design and a comparison with the restricted Continual Reassessment Method. Pharm Stat. 2019;18 (6):659-670. doi: 10.1002/pst.1955. PubMed PMID:31237419 PubMed Central PMC8932137.
  174. Kote-Jarai, Z, Leongamornlert, DA, Saunders, EJ, Conti, DV, Eeles, RA. Reply to Xiaoling Lin, Brian T. Helfand, and Jianfeng Xu's Letter to the Editor re: Daniel A. Leongamornlert, Edward J. Saunders, Sarah Wakerell, et al. Germline DNA Repair Gene Mutations in Young-onset Prostate Cancer Cases in the UK: Evidence for a More Extensive Genetic Panel. Eur Urol 2019;76:329-37. Eur Urol. 2019;76 (5):e130-e131. doi: 10.1016/j.eururo.2019.06.012. PubMed PMID:31235193 .
  175. Du, Z, Hopp, H, Ingles, SA, Huff, C, Sheng, X, Weaver, B et al.. A genome-wide association study of prostate cancer in Latinos. Int J Cancer. 2020;146 (7):1819-1826. doi: 10.1002/ijc.32525. PubMed PMID:31226226 PubMed Central PMC7028127.
  176. Lopez-Soler, RI, Patel, SK, Lyubarova, R, Pashkovetsky, E, Wang, S, Schuster, D et al.. Pericardial Effusion Associated With Sirolimus Use After Renal Transplantation: A Single-Center Case Series. Transplant Proc. 2019;51 (6):1739-1743. doi: 10.1016/j.transproceed.2019.04.043. PubMed PMID:31204020 .
  177. Law, PJ, Timofeeva, M, Fernandez-Rozadilla, C, Broderick, P, Studd, J, Fernandez-Tajes, J et al.. Association analyses identify 31 new risk loci for colorectal cancer susceptibility. Nat Commun. 2019;10 (1):2154. doi: 10.1038/s41467-019-09775-w. PubMed PMID:31089142 PubMed Central PMC6517433.
  178. Xu, S, Gilliland, FD, Conti, DV. Elucidation of causal direction between asthma and obesity: a bi-directional Mendelian randomization study. Int J Epidemiol. 2019;48 (3):899-907. doi: 10.1093/ije/dyz070. PubMed PMID:31005996 PubMed Central PMC6659368.
  179. Chiu, V, Hogen, R, Sher, L, Wadé, N, Conti, D, Martynova, A et al.. Telomerase Variants in Patients with Cirrhosis Awaiting Liver Transplantation. Hepatology. 2019;69 (6):2652-2663. doi: 10.1002/hep.30557. PubMed PMID:30964210 PubMed Central PMC6594079.
  180. Alderete, TL, Jin, R, Walker, DI, Valvi, D, Chen, Z, Jones, DP et al.. Perfluoroalkyl substances, metabolomic profiling, and alterations in glucose homeostasis among overweight and obese Hispanic children: A proof-of-concept analysis. Environ Int. 2019;126 :445-453. doi: 10.1016/j.envint.2019.02.047. PubMed PMID:30844580 PubMed Central PMC6555482.
  181. Mijuskovic, M, Saunders, EJ, Leongamornlert, DA, Wakerell, S, Whitmore, I, Dadaev, T et al.. Correction: Rare germline variants in DNA repair genes and the angiogenesis pathway predispose prostate cancer patients to develop metastatic disease. Br J Cancer. 2019;120 (8):867. doi: 10.1038/s41416-019-0419-4. PubMed PMID:30837682 PubMed Central PMC6474270.
  182. Bien, SA, Su, YR, Conti, DV, Harrison, TA, Qu, C, Guo, X et al.. Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer. Hum Genet. 2019;138 (4):307-326. doi: 10.1007/s00439-019-01989-8. PubMed PMID:30820706 PubMed Central PMC6483948.
  183. Leongamornlert, DA, Saunders, EJ, Wakerell, S, Whitmore, I, Dadaev, T, Cieza-Borrella, C et al.. Germline DNA Repair Gene Mutations in Young-onset Prostate Cancer Cases in the UK: Evidence for a More Extensive Genetic Panel. Eur Urol. 2019;76 (3):329-337. doi: 10.1016/j.eururo.2019.01.050. PubMed PMID:30777372 PubMed Central PMC6695475.
  184. Jiang, X, Finucane, HK, Schumacher, FR, Schmit, SL, Tyrer, JP, Han, Y et al.. Shared heritability and functional enrichment across six solid cancers. Nat Commun. 2019;10 (1):431. doi: 10.1038/s41467-018-08054-4. PubMed PMID:30683880 PubMed Central PMC6347624.
  185. Wang, J, Van Den Berg, D, Hwang, AE, Weisenberger, D, Triche, T, Nathwani, BN et al.. DNA methylation patterns of adult survivors of adolescent/young adult Hodgkin lymphoma compared to their unaffected monozygotic twin. Leuk Lymphoma. 2019;60 (6):1429-1437. doi: 10.1080/10428194.2018.1533128. PubMed PMID:30668190 PubMed Central PMC7781082.
  186. Vijayakrishnan, J, Studd, J, Broderick, P, Kinnersley, B, Holroyd, A, Law, PJ et al.. Author Correction: Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia. Nat Commun. 2019;10 (1):419. doi: 10.1038/s41467-018-08106-9. PubMed PMID:30664635 PubMed Central PMC6341085.
  187. Matejcic, M, Saunders, EJ, Dadaev, T, Brook, MN, Wang, K, Sheng, X et al.. Author Correction: Germline variation at 8q24 and prostate cancer risk in men of European ancestry. Nat Commun. 2019;10 (1):382. doi: 10.1038/s41467-019-08293-z. PubMed PMID:30655571 PubMed Central PMC6336778.
  188. Gauderman, WJ, Kim, A, Conti, DV, Morrison, J, Thomas, DC, Vora, H et al.. A Unified Model for the Analysis of Gene-Environment Interaction. Am J Epidemiol. 2019;188 (4):760-767. doi: 10.1093/aje/kwy278. PubMed PMID:30649161 PubMed Central PMC6438805.
  189. Went, M, Sud, A, Försti, A, Halvarsson, BM, Weinhold, N, Kimber, S et al.. Author Correction: Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma. Nat Commun. 2019;10 (1):213. doi: 10.1038/s41467-018-08107-8. PubMed PMID:30631080 PubMed Central PMC6328616.
  190. Schumacher, FR, Olama, AAA, Berndt, SI, Benlloch, S, Ahmed, M, Saunders, EJ et al.. Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. Nat Genet. 2019;51 (2):363. doi: 10.1038/s41588-018-0330-6. PubMed PMID:30622367 .
  191. Sud, A, Thomsen, H, Law, PJ, Försti, A, da Silva Filho, MI, Holroyd, A et al.. Author Correction: Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility. Nat Commun. 2019;10 (1):157. doi: 10.1038/s41467-018-08105-w. PubMed PMID:30622283 PubMed Central PMC6325156.
  192. Mancuso, N, Gayther, S, Gusev, A, Zheng, W, Penney, KL, PRACTICAL consortium et al.. Author Correction: Large-scale transcriptome-wide association study identifies new prostate cancer risk regions. Nat Commun. 2019;10 (1):171. doi: 10.1038/s41467-018-08108-7. PubMed PMID:30622272 PubMed Central PMC6325152.
  193. Lu, Y, Kweon, SS, Tanikawa, C, Jia, WH, Xiang, YB, Cai, Q et al.. Large-Scale Genome-Wide Association Study of East Asians Identifies Loci Associated With Risk for Colorectal Cancer. Gastroenterology. 2019;156 (5):1455-1466. doi: 10.1053/j.gastro.2018.11.066. PubMed PMID:30529582 PubMed Central PMC6441622.
  194. Asante, I, Pei, H, Zhou, E, Liu, S, Chui, D, Yoo, E et al.. Exploratory metabolomic study to identify blood-based biomarkers as a potential screen for colorectal cancer. Mol Omics. 2019;15 (1):21-29. doi: 10.1039/c8mo00158h. PubMed PMID:30515501 PubMed Central PMC6413524.
  195. Huyghe, JR, Bien, SA, Harrison, TA, Kang, HM, Chen, S, Schmit, SL et al.. Discovery of common and rare genetic risk variants for colorectal cancer. Nat Genet. 2019;51 (1):76-87. doi: 10.1038/s41588-018-0286-6. PubMed PMID:30510241 PubMed Central PMC6358437.
  196. Amezcua, L, Beecham, AH, Delgado, SR, Chinea, A, Burnett, M, Manrique, CP et al.. Native ancestry is associated with optic neuritis and age of onset in hispanics with multiple sclerosis. Ann Clin Transl Neurol. 2018;5 (11):1362-1371. doi: 10.1002/acn3.646. PubMed PMID:30480030 PubMed Central PMC6243381.
  197. Moss, LC, Gauderman, WJ, Lewinger, JP, Conti, DV. Using Bayes model averaging to leverage both gene main effects and G ×  E interactions to identify genomic regions in genome-wide association studies. Genet Epidemiol. 2019;43 (2):150-165. doi: 10.1002/gepi.22171. PubMed PMID:30456811 PubMed Central PMC6375769.
  198. Wang, SC, Garcia, R, Torosoff, M, Fein, SA, Ashar, A, Chandolias, N et al.. Influence of mildly and moderately elevated pulmonary artery systolic pressure on post-renal transplantation survival and graft function. Echocardiography. 2019;36 (1):22-27. doi: 10.1111/echo.14192. PubMed PMID:30411400 .
  199. Matejcic, M, Saunders, EJ, Dadaev, T, Brook, MN, Wang, K, Sheng, X et al.. Germline variation at 8q24 and prostate cancer risk in men of European ancestry. Nat Commun. 2018;9 (1):4616. doi: 10.1038/s41467-018-06863-1. PubMed PMID:30397198 PubMed Central PMC6218483.
  200. Adams, CD, Richmond, R, Ferreira, DLS, Spiller, W, Tan, V, Zheng, J et al.. Circulating Metabolic Biomarkers of Screen-Detected Prostate Cancer in the ProtecT Study. Cancer Epidemiol Biomarkers Prev. 2019;28 (1):208-216. doi: 10.1158/1055-9965.EPI-18-0079. PubMed PMID:30352818 PubMed Central PMC6746173.
  201. Mancuso, N, Gayther, S, Gusev, A, Zheng, W, Penney, KL, Kote-Jarai, Z et al.. Large-scale transcriptome-wide association study identifies new prostate cancer risk regions. Nat Commun. 2018;9 (1):4079. doi: 10.1038/s41467-018-06302-1. PubMed PMID:30287866 PubMed Central PMC6172280.
  202. Went, M, Sud, A, Försti, A, Halvarsson, BM, Weinhold, N, Kimber, S et al.. Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma. Nat Commun. 2018;9 (1):3707. doi: 10.1038/s41467-018-04989-w. PubMed PMID:30213928 PubMed Central PMC6137048.
  203. Gignoux, CR, Torgerson, DG, Pino-Yanes, M, Uricchio, LH, Galanter, J, Roth, LA et al.. An admixture mapping meta-analysis implicates genetic variation at 18q21 with asthma susceptibility in Latinos. J Allergy Clin Immunol. 2019;143 (3):957-969. doi: 10.1016/j.jaci.2016.08.057. PubMed PMID:30201514 PubMed Central PMC6927816.
  204. Hwang, AE, Marshall, V, Conti, DV, Nathwani, BN, Mack, TM, Whitby, D et al.. Epstein-Barr virus load is higher in long-term Hodgkin lymphoma survivors compared to their unaffected twins and unrelated controls. Br J Haematol. 2019;185 (2):377-380. doi: 10.1111/bjh.15522. PubMed PMID:30117152 .
  205. Schmit, SL, Edlund, CK, Schumacher, FR, Gong, J, Harrison, TA, Huyghe, JR et al.. Novel Common Genetic Susceptibility Loci for Colorectal Cancer. J Natl Cancer Inst. 2019;111 (2):146-157. doi: 10.1093/jnci/djy099. PubMed PMID:29917119 PubMed Central PMC6555904.
  206. Mijuskovic, M, Saunders, EJ, Leongamornlert, DA, Wakerell, S, Whitmore, I, Dadaev, T et al.. Rare germline variants in DNA repair genes and the angiogenesis pathway predispose prostate cancer patients to develop metastatic disease. Br J Cancer. 2018;119 (1):96-104. doi: 10.1038/s41416-018-0141-7. PubMed PMID:29915322 PubMed Central PMC6035259.
  207. Dadaev, T, Saunders, EJ, Newcombe, PJ, Anokian, E, Leongamornlert, DA, Brook, MN et al.. Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants. Nat Commun. 2018;9 (1):2256. doi: 10.1038/s41467-018-04109-8. PubMed PMID:29892050 PubMed Central PMC5995836.
  208. Schumacher, FR, Al Olama, AA, Berndt, SI, Benlloch, S, Ahmed, M, Saunders, EJ et al.. Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. Nat Genet. 2018;50 (7):928-936. doi: 10.1038/s41588-018-0142-8. PubMed PMID:29892016 PubMed Central PMC6568012.
  209. Ke, W, Rand, KA, Conti, DV, Setiawan, VW, Stram, DO, Wilkens, L et al.. Evaluation of 71 Coronary Artery Disease Risk Variants in a Multiethnic Cohort. Front Cardiovasc Med. 2018;5 :19. doi: 10.3389/fcvm.2018.00019. PubMed PMID:29740590 PubMed Central PMC5931137.
  210. Vijayakrishnan, J, Studd, J, Broderick, P, Kinnersley, B, Holroyd, A, Law, PJ et al.. Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia. Nat Commun. 2018;9 (1):1340. doi: 10.1038/s41467-018-03178-z. PubMed PMID:29632299 PubMed Central PMC5890276.
  211. Reiner, AS, Sisti, J, John, EM, Lynch, CF, Brooks, JD, Mellemkjær, L et al.. Breast Cancer Family History and Contralateral Breast Cancer Risk in Young Women: An Update From the Women's Environmental Cancer and Radiation Epidemiology Study. J Clin Oncol. 2018;36 (15):1513-1520. doi: 10.1200/JCO.2017.77.3424. PubMed PMID:29620998 PubMed Central PMC5959199.
  212. Du, Z, Lubmawa, A, Gundell, S, Wan, P, Nalukenge, C, Muwanga, P et al.. Genetic risk of prostate cancer in Ugandan men. Prostate. 2018;78 (5):370-376. doi: 10.1002/pros.23481. PubMed PMID:29356057 PubMed Central PMC7534689.
  213. Sud, A, Thomsen, H, Law, PJ, Försti, A, Filho, MIDS, Holroyd, A et al.. Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility. Nat Commun. 2017;8 (1):1892. doi: 10.1038/s41467-017-00320-1. PubMed PMID:29196614 PubMed Central PMC5711884.
  214. Higgins, SP, Tang, Y, Higgins, CE, Mian, B, Zhang, W, Czekay, RP et al.. TGF-β1/p53 signaling in renal fibrogenesis. Cell Signal. 2018;43 :1-10. doi: 10.1016/j.cellsig.2017.11.005. PubMed PMID:29191563 PubMed Central PMC5860677.
  215. Conti, DV, Wang, K, Sheng, X, Bensen, JT, Hazelett, DJ, Cook, MB et al.. Two Novel Susceptibility Loci for Prostate Cancer in Men of African Ancestry. J Natl Cancer Inst. 2017;109 (8):. doi: 10.1093/jnci/djx084. PubMed PMID:29117387 PubMed Central PMC5448553.
  216. McAllister, K, Mechanic, LE, Amos, C, Aschard, H, Blair, IA, Chatterjee, N et al.. Current Challenges and New Opportunities for Gene-Environment Interaction Studies of Complex Diseases. Am J Epidemiol. 2017;186 (7):753-761. doi: 10.1093/aje/kwx227. PubMed PMID:28978193 PubMed Central PMC5860428.
  217. Gauderman, WJ, Mukherjee, B, Aschard, H, Hsu, L, Lewinger, JP, Patel, CJ et al.. Update on the State of the Science for Analytical Methods for Gene-Environment Interactions. Am J Epidemiol. 2017;186 (7):762-770. doi: 10.1093/aje/kwx228. PubMed PMID:28978192 PubMed Central PMC5859988.
  218. Ritchie, MD, Davis, JR, Aschard, H, Battle, A, Conti, D, Du, M et al.. Incorporation of Biological Knowledge Into the Study of Gene-Environment Interactions. Am J Epidemiol. 2017;186 (7):771-777. doi: 10.1093/aje/kwx229. PubMed PMID:28978191 PubMed Central PMC5860556.
  219. Tanskanen, T, van den Berg, L, Välimäki, N, Aavikko, M, Ness-Jensen, E, Hveem, K et al.. Genome-wide association study and meta-analysis in Northern European populations replicate multiple colorectal cancer risk loci. Int J Cancer. 2018;142 (3):540-546. doi: 10.1002/ijc.31076. PubMed PMID:28960316 PubMed Central PMC6383773.
  220. May-Wilson, S, Sud, A, Law, PJ, Palin, K, Tuupanen, S, Gylfe, A et al.. Pro-inflammatory fatty acid profile and colorectal cancer risk: A Mendelian randomisation analysis. Eur J Cancer. 2017;84 :228-238. doi: 10.1016/j.ejca.2017.07.034. PubMed PMID:28829991 PubMed Central PMC5630201.
  221. Jourd'heuil, FL, Xu, H, Reilly, T, McKellar, K, El Alaoui, C, Steppich, J et al.. The Hemoglobin Homolog Cytoglobin in Smooth Muscle Inhibits Apoptosis and Regulates Vascular Remodeling. Arterioscler Thromb Vasc Biol. 2017;37 (10):1944-1955. doi: 10.1161/ATVBAHA.117.309410. PubMed PMID:28798140 PubMed Central PMC5620122.
  222. Feng, YA, Cho, K, Lindstrom, S, Kraft, P, Cormack, J, IGAP Consortium, Colorectal Transdisciplinary Study (CORECT) et al.. Investigating the genetic relationship between Alzheimer's disease and cancer using GWAS summary statistics. Hum Genet. 2017;136 (10):1341-1351. doi: 10.1007/s00439-017-1831-6. PubMed PMID:28780673 PubMed Central PMC5693762.
  223. International Obsessive Compulsive Disorder Foundation Genetics Collaborative (IOCDF-GC) and OCD Collaborative Genetics Association Studies (OCGAS). Revealing the complex genetic architecture of obsessive-compulsive disorder using meta-analysis. Mol Psychiatry. 2018;23 (5):1181-1188. doi: 10.1038/mp.2017.154. PubMed PMID:28761083 PubMed Central PMC6660151.
  224. Gu, F, Zhang, H, Hyland, PL, Berndt, S, Gapstur, SM, Wheeler, W et al.. Inherited variation in circadian rhythm genes and risks of prostate cancer and three other cancer sites in combined cancer consortia. Int J Cancer. 2017;141 (9):1794-1802. doi: 10.1002/ijc.30883. PubMed PMID:28699174 PubMed Central PMC5907928.
  225. Lindström, S, Finucane, H, Bulik-Sullivan, B, Schumacher, FR, Amos, CI, Hung, RJ et al.. Quantifying the Genetic Correlation between Multiple Cancer Types. Cancer Epidemiol Biomarkers Prev. 2017;26 (9):1427-1435. doi: 10.1158/1055-9965.EPI-17-0211. PubMed PMID:28637796 PubMed Central PMC5582139.
  226. Ng, MCY, Graff, M, Lu, Y, Justice, AE, Mudgal, P, Liu, CT et al.. Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium. PLoS Genet. 2017;13 (4):e1006719. doi: 10.1371/journal.pgen.1006719. PubMed PMID:28430825 PubMed Central PMC5419579.
  227. Feng, Y, Rhie, SK, Huo, D, Ruiz-Narvaez, EA, Haddad, SA, Ambrosone, CB et al.. Characterizing Genetic Susceptibility to Breast Cancer in Women of African Ancestry. Cancer Epidemiol Biomarkers Prev. 2017;26 (7):1016-1026. doi: 10.1158/1055-9965.EPI-16-0567. PubMed PMID:28377418 PubMed Central PMC5500414.
  228. Zhao, J, Jourd'heuil, FL, Xue, M, Conti, D, Lopez-Soler, RI, Ginnan, R et al.. Dual Function for Mature Vascular Smooth Muscle Cells During Arteriovenous Fistula Remodeling. J Am Heart Assoc. 2017;6 (4):. doi: 10.1161/JAHA.116.004891. PubMed PMID:28360226 PubMed Central PMC5533005.
  229. Rodriguez-Broadbent, H, Law, PJ, Sud, A, Palin, K, Tuupanen, S, Gylfe, A et al.. Mendelian randomisation implicates hyperlipidaemia as a risk factor for colorectal cancer. Int J Cancer. 2017;140 (12):2701-2708. doi: 10.1002/ijc.30709. PubMed PMID:28340513 PubMed Central PMC6135234.
  230. Wang, H, Schmit, SL, Haiman, CA, Keku, TO, Kato, I, Palmer, JR et al.. Novel colon cancer susceptibility variants identified from a genome-wide association study in African Americans. Int J Cancer. 2017;140 (12):2728-2733. doi: 10.1002/ijc.30687. PubMed PMID:28295283 PubMed Central PMC5505639.
  231. Lopez-Soler, RI, Chan, R, Martinolich, J, Park, L, Ata, A, Chandolias, N et al.. Early steroid withdrawal results in improved patient and graft survival and lower risk of post-transplant cardiovascular risk profiles: A single-center 10-year experience. Clin Transplant. 2017;31 (2):. doi: 10.1111/ctr.12878. PubMed PMID:27888534 .
  232. Orlando, G, Law, PJ, Palin, K, Tuupanen, S, Gylfe, A, Hänninen, UA et al.. Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease. Hum Mol Genet. 2016;25 (11):2349-2359. doi: 10.1093/hmg/ddw087. PubMed PMID:27005424 PubMed Central PMC5081051.
  233. Hahn, AB, Mackey, M, Constantino, D, Ata, A, Chandolias, N, Lopez-Soler, R et al.. The new kidney allocation system does not equally advantage all very high cPRA candidates - A single center analysis. Hum Immunol. 2017;78 (1):37-40. doi: 10.1016/j.humimm.2016.10.010. PubMed PMID:27771384 .
  234. Amos, CI, Dennis, J, Wang, Z, Byun, J, Schumacher, FR, Gayther, SA et al.. The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers. Cancer Epidemiol Biomarkers Prev. 2017;26 (1):126-135. doi: 10.1158/1055-9965.EPI-16-0106. PubMed PMID:27697780 PubMed Central PMC5224974.
  235. Rand, KA, Song, C, Dean, E, Serie, DJ, Curtin, K, Sheng, X et al.. A Meta-analysis of Multiple Myeloma Risk Regions in African and European Ancestry Populations Identifies Putatively Functional Loci. Cancer Epidemiol Biomarkers Prev. 2016;25 (12):1609-1618. doi: 10.1158/1055-9965.EPI-15-1193. PubMed PMID:27587788 PubMed Central PMC5524541.
  236. Yang, B, Thrift, AP, Figueiredo, JC, Jenkins, MA, Schumacher, FR, Conti, DV et al.. Common variants in the obesity-associated genes FTO and MC4R are not associated with risk of colorectal cancer. Cancer Epidemiol. 2016;44 :1-4. doi: 10.1016/j.canep.2016.07.003. PubMed PMID:27449576 PubMed Central PMC5125024.
  237. Du, M, Jiao, S, Bien, SA, Gala, M, Abecasis, G, Bezieau, S et al.. Fine-Mapping of Common Genetic Variants Associated with Colorectal Tumor Risk Identified Potential Functional Variants. PLoS One. 2016;11 (7):e0157521. doi: 10.1371/journal.pone.0157521. PubMed PMID:27379672 PubMed Central PMC4933364.
  238. Jarvis, D, Mitchell, JS, Law, PJ, Palin, K, Tuupanen, S, Gylfe, A et al.. Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer. Br J Cancer. 2016;115 (2):266-72. doi: 10.1038/bjc.2016.188. PubMed PMID:27336604 PubMed Central PMC4947703.
  239. Zhang, P, Lewinger, JP, Conti, D, Morrison, JL, Gauderman, WJ. Detecting Gene-Environment Interactions for a Quantitative Trait in a Genome-Wide Association Study. Genet Epidemiol. 2016;40 (5):394-403. doi: 10.1002/gepi.21977. PubMed PMID:27230133 PubMed Central PMC5108681.
  240. Schmit, SL, Schumacher, FR, Edlund, CK, Conti, DV, Ihenacho, U, Wan, P et al.. Genome-wide association study of colorectal cancer in Hispanics. Carcinogenesis. 2016;37 (6):547-556. doi: 10.1093/carcin/bgw046. PubMed PMID:27207650 PubMed Central PMC4876992.
  241. Fehringer, G, Kraft, P, Pharoah, PD, Eeles, RA, Chatterjee, N, Schumacher, FR et al.. Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations. Cancer Res. 2016;76 (17):5103-14. doi: 10.1158/0008-5472.CAN-15-2980. PubMed PMID:27197191 PubMed Central PMC5010493.
  242. Baurley, JW, Edlund, CK, Pardamean, CI, Conti, DV, Krasnow, R, Javitz, HS et al.. Genome-Wide Association of the Laboratory-Based Nicotine Metabolite Ratio in Three Ancestries. Nicotine Tob Res. 2016;18 (9):1837-1844. doi: 10.1093/ntr/ntw117. PubMed PMID:27113016 PubMed Central PMC4978985.
  243. Gusev, A, Shi, H, Kichaev, G, Pomerantz, M, Li, F, Long, HW et al.. Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation. Nat Commun. 2016;7 :10979. doi: 10.1038/ncomms10979. PubMed PMID:27052111 PubMed Central PMC4829663.
  244. Newcombe, PJ, Conti, DV, Richardson, S. JAM: A Scalable Bayesian Framework for Joint Analysis of Marginal SNP Effects. Genet Epidemiol. 2016;40 (3):188-201. doi: 10.1002/gepi.21953. PubMed PMID:27027514 PubMed Central PMC4817278.
  245. Zeng, C, Matsuda, K, Jia, WH, Chang, J, Kweon, SS, Xiang, YB et al.. Identification of Susceptibility Loci and Genes for Colorectal Cancer Risk. Gastroenterology. 2016;150 (7):1633-1645. doi: 10.1053/j.gastro.2016.02.076. PubMed PMID:26965516 PubMed Central PMC4909543.
  246. Salomon, MP, Li, WL, Edlund, CK, Morrison, J, Fortini, BK, Win, AK et al.. GWASeq: targeted re-sequencing follow up to GWAS. BMC Genomics. 2016;17 :176. doi: 10.1186/s12864-016-2459-y. PubMed PMID:26940994 PubMed Central PMC4776370.
  247. Baurley, JW, Edlund, CK, Pardamean, CI, Conti, DV, Bergen, AW. Smokescreen: a targeted genotyping array for addiction research. BMC Genomics. 2016;17 :145. doi: 10.1186/s12864-016-2495-7. PubMed PMID:26921259 PubMed Central PMC4769529.
  248. Han, Y, Rand, KA, Hazelett, DJ, Ingles, SA, Kittles, RA, Strom, SS et al.. Prostate Cancer Susceptibility in Men of African Ancestry at 8q24. J Natl Cancer Inst. 2016;108 (7):. doi: 10.1093/jnci/djv431. PubMed PMID:26823525 PubMed Central PMC4948565.
  249. Hazelett, DJ, Conti, DV, Han, Y, Al Olama, AA, Easton, D, Eeles, RA et al.. Reducing GWAS Complexity. Cell Cycle. 2016;15 (1):22-4. doi: 10.1080/15384101.2015.1120928. PubMed PMID:26771711 PubMed Central PMC4825730.
  250. Figueroa, JD, Middlebrooks, CD, Banday, AR, Ye, Y, Garcia-Closas, M, Chatterjee, N et al.. Identification of a novel susceptibility locus at 13q34 and refinement of the 20p12.2 region as a multi-signal locus associated with bladder cancer risk in individuals of European ancestry. Hum Mol Genet. 2016;25 (6):1203-14. doi: 10.1093/hmg/ddv492. PubMed PMID:26732427 PubMed Central PMC4817084.
  251. Cheng, TH, Thompson, D, Painter, J, O'Mara, T, Gorman, M, Martin, L et al.. Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1. Sci Rep. 2015;5 :17369. doi: 10.1038/srep17369. PubMed PMID:26621817 PubMed Central PMC4664893.
  252. Rand, KA, Rohland, N, Tandon, A, Stram, A, Sheng, X, Do, R et al.. Whole-exome sequencing of over 4100 men of African ancestry and prostate cancer risk. Hum Mol Genet. 2016;25 (2):371-81. doi: 10.1093/hmg/ddv462. PubMed PMID:26604137 PubMed Central PMC4865031.
  253. Mancuso, N, Rohland, N, Rand, KA, Tandon, A, Allen, A, Quinque, D et al.. The contribution of rare variation to prostate cancer heritability. Nat Genet. 2016;48 (1):30-5. doi: 10.1038/ng.3446. PubMed PMID:26569126 PubMed Central PMC7534691.
  254. Schumacher, FR, Schmit, SL, Jiao, S, Edlund, CK, Wang, H, Zhang, B et al.. Corrigendum: genome-wide association study of colorectal cancer identifies six new susceptibility loci. Nat Commun. 2015;6 :8739. doi: 10.1038/ncomms9739. PubMed PMID:26498495 .
  255. Sampson, JN, Wheeler, WA, Yeager, M, Panagiotou, O, Wang, Z, Berndt, SI et al.. Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for Thirteen Cancer Types. J Natl Cancer Inst. 2015;107 (12):djv279. doi: 10.1093/jnci/djv279. PubMed PMID:26464424 PubMed Central PMC4806328.
  256. Ramus, SJ, Song, H, Dicks, E, Tyrer, JP, Rosenthal, AN, Intermaggio, MP et al.. Germline Mutations in the BRIP1, BARD1, PALB2, and NBN Genes in Women With Ovarian Cancer. J Natl Cancer Inst. 2015;107 (11):. doi: 10.1093/jnci/djv214. PubMed PMID:26315354 PubMed Central PMC4643629.
  257. Song, H, Dicks, E, Ramus, SJ, Tyrer, JP, Intermaggio, MP, Hayward, J et al.. Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population. J Clin Oncol. 2015;33 (26):2901-7. doi: 10.1200/JCO.2015.61.2408. PubMed PMID:26261251 PubMed Central PMC4554751.
  258. Al-Tassan, NA, Whiffin, N, Hosking, FJ, Palles, C, Farrington, SM, Dobbins, SE et al.. Erratum: A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer. Sci Rep. 2015;5 :12372. doi: 10.1038/srep12372. PubMed PMID:26237130 PubMed Central PMC4523102.
  259. Han, Y, Hazelett, DJ, Wiklund, F, Schumacher, FR, Stram, DO, Berndt, SI et al.. Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions. Hum Mol Genet. 2015;24 (19):5603-18. doi: 10.1093/hmg/ddv269. PubMed PMID:26162851 PubMed Central PMC4572069.
  260. Schumacher, FR, Schmit, SL, Jiao, S, Edlund, CK, Wang, H, Zhang, B et al.. Genome-wide association study of colorectal cancer identifies six new susceptibility loci. Nat Commun. 2015;6 :7138. doi: 10.1038/ncomms8138. PubMed PMID:26151821 PubMed Central PMC4967357.
  261. Bergen, AW, Michel, M, Nishita, D, Krasnow, R, Javitz, HS, Conneely, KN et al.. Drug Metabolizing Enzyme and Transporter Gene Variation, Nicotine Metabolism, Prospective Abstinence, and Cigarette Consumption. PLoS One. 2015;10 (7):e0126113. doi: 10.1371/journal.pone.0126113. PubMed PMID:26132489 PubMed Central PMC4488893.
  262. Khalili, H, Gong, J, Brenner, H, Austin, TR, Hutter, CM, Baba, Y et al.. Identification of a common variant with potential pleiotropic effect on risk of inflammatory bowel disease and colorectal cancer. Carcinogenesis. 2015;36 (9):999-1007. doi: 10.1093/carcin/bgv086. PubMed PMID:26071399 PubMed Central PMC4573660.
  263. Amin Al Olama, A, Dadaev, T, Hazelett, DJ, Li, Q, Leongamornlert, D, Saunders, EJ et al.. Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans. Hum Mol Genet. 2015;24 (19):5589-602. doi: 10.1093/hmg/ddv203. PubMed PMID:26025378 PubMed Central PMC4572072.
  264. Al-Tassan, NA, Whiffin, N, Hosking, FJ, Palles, C, Farrington, SM, Dobbins, SE et al.. A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer. Sci Rep. 2015;5 :10442. doi: 10.1038/srep10442. PubMed PMID:25990418 PubMed Central PMC4438486.
  265. Yang, J, Zhao, X, Patel, A, Potru, R, Azizi-Ghannad, S, Dolinger, M et al.. Rapamycin Inhibition of mTOR Reduces Levels of the Na+/H+ Exchanger 3 in Intestines of Mice and Humans, Leading to Diarrhea. Gastroenterology. 2015;149 (1):151-62. doi: 10.1053/j.gastro.2015.03.046. PubMed PMID:25836987 PubMed Central PMC4849539.
  266. Jeong, S, Patel, N, Edlund, CK, Hartiala, J, Hazelett, DJ, Itakura, T et al.. Identification of a Novel Mucin Gene HCG22 Associated With Steroid-Induced Ocular Hypertension. Invest Ophthalmol Vis Sci. 2015;56 (4):2737-48. doi: 10.1167/iovs.14-14803. PubMed PMID:25813999 PubMed Central PMC4416661.
  267. Amezcua, L, Conti, DV, Liu, L, Ledezma, K, Langer-Goulda, AM. Place of birth,age of immigration,and disability in Hispanics with multiple sclerosis. Mult Scler Relat Disord. 2015;4 (1):25-30. doi: 10.1016/j.msard.2014.11.008. PubMed PMID:25729639 PubMed Central PMC4341972.
  268. Green, M, Covington, S, Taranto, S, Wolfe, C, Bell, W, Biggins, SW et al.. Donor-derived transmission events in 2013: a report of the Organ Procurement Transplant Network Ad Hoc Disease Transmission Advisory Committee. Transplantation. 2015;99 (2):282-7. doi: 10.1097/TP.0000000000000584. PubMed PMID:25594557 .
  269. Weir, MR, Gravens-Muller, L, Costa, N, Ivanova, A, Manitpisitkul, W, Bostom, AG et al.. Safety events in kidney transplant recipients: results from the folic Acid for vascular outcome reduction in transplant trial. Transplantation. 2015;99 (5):1003-8. doi: 10.1097/TP.0000000000000454. PubMed PMID:25393158 PubMed Central PMC4469189.
  270. Fu, YP, Kohaar, I, Moore, LE, Lenz, P, Figueroa, JD, Tang, W et al.. The 19q12 bladder cancer GWAS signal: association with cyclin E function and aggressive disease. Cancer Res. 2014;74 (20):5808-18. doi: 10.1158/0008-5472.CAN-14-1531. PubMed PMID:25320178 PubMed Central PMC4203382.
  271. Pino-Yanes, M, Thakur, N, Gignoux, CR, Galanter, JM, Roth, LA, Eng, C et al.. Genetic ancestry influences asthma susceptibility and lung function among Latinos. J Allergy Clin Immunol. 2015;135 (1):228-35. doi: 10.1016/j.jaci.2014.07.053. PubMed PMID:25301036 PubMed Central PMC4289103.
  272. Wassenaar, CA, Conti, DV, Das, S, Chen, P, Cook, EH, Ratain, MJ et al.. UGT1A and UGT2B genetic variation alters nicotine and nitrosamine glucuronidation in european and african american smokers. Cancer Epidemiol Biomarkers Prev. 2015;24 (1):94-104. doi: 10.1158/1055-9965.EPI-14-0804. PubMed PMID:25277794 PubMed Central PMC4294984.
  273. Guo, Y, Conti, DV, Wang, K. Enlight: web-based integration of GWAS results with biological annotations. Bioinformatics. 2015;31 (2):275-6. doi: 10.1093/bioinformatics/btu639. PubMed PMID:25262152 PubMed Central PMC4287951.
  274. Al Olama, AA, Kote-Jarai, Z, Berndt, SI, Conti, DV, Schumacher, F, Han, Y et al.. A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer. Nat Genet. 2014;46 (10):1103-9. doi: 10.1038/ng.3094. PubMed PMID:25217961 PubMed Central PMC4383163.
  275. Yu, D, Mathews, CA, Scharf, JM, Neale, BM, Davis, LK, Gamazon, ER et al.. Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD. Am J Psychiatry. 2015;172 (1):82-93. doi: 10.1176/appi.ajp.2014.13101306. PubMed PMID:25158072 PubMed Central PMC4282594.
  276. Bergen, AW, Javitz, HS, Krasnow, R, Michel, M, Nishita, D, Conti, DV et al.. Organic cation transporter variation and response to smoking cessation therapies. Nicotine Tob Res. 2014;16 (12):1638-46. doi: 10.1093/ntr/ntu161. PubMed PMID:25143296 PubMed Central PMC4296186.
  277. Wang, H, Burnett, T, Kono, S, Haiman, CA, Iwasaki, M, Wilkens, LR et al.. Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A. Nat Commun. 2014;5 :4613. doi: 10.1038/ncomms5613. PubMed PMID:25105248 PubMed Central PMC4180879.
  278. Han, Y, Signorello, LB, Strom, SS, Kittles, RA, Rybicki, BA, Stanford, JL et al.. Generalizability of established prostate cancer risk variants in men of African ancestry. Int J Cancer. 2015;136 (5):1210-7. doi: 10.1002/ijc.29066. PubMed PMID:25044450 PubMed Central PMC4268262.
  279. Wang, Z, Zhu, B, Zhang, M, Parikh, H, Jia, J, Chung, CC et al.. Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33. Hum Mol Genet. 2014;23 (24):6616-33. doi: 10.1093/hmg/ddu363. PubMed PMID:25027329 PubMed Central PMC4240198.
  280. Schmit, SL, Schumacher, FR, Edlund, CK, Conti, DV, Raskin, L, Lejbkowicz, F et al.. A novel colorectal cancer risk locus at 4q32.2 identified from an international genome-wide association study. Carcinogenesis. 2014;35 (11):2512-9. doi: 10.1093/carcin/bgu148. PubMed PMID:25023989 PubMed Central PMC4271131.
  281. Feng, Y, Stram, DO, Rhie, SK, Millikan, RC, Ambrosone, CB, John, EM et al.. A comprehensive examination of breast cancer risk loci in African American women. Hum Mol Genet. 2014;23 (20):5518-26. doi: 10.1093/hmg/ddu252. PubMed PMID:24852375 PubMed Central PMC4168823.
  282. Zhang, B, Jia, WH, Matsuda, K, Kweon, SS, Matsuo, K, Xiang, YB et al.. Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk. Nat Genet. 2014;46 (6):533-42. doi: 10.1038/ng.2985. PubMed PMID:24836286 PubMed Central PMC4068797.
  283. Cheng, TH, Gorman, M, Martin, L, Barclay, E, Casey, G, Colon Cancer Family Registry et al.. Common colorectal cancer risk alleles contribute to the multiple colorectal adenoma phenotype, but do not influence colonic polyposis in FAP. Eur J Hum Genet. 2015;23 (2):260-3. doi: 10.1038/ejhg.2014.74. PubMed PMID:24801760 PubMed Central PMC4140766.
  284. Whiffin, N, Hosking, FJ, Farrington, SM, Palles, C, Dobbins, SE, Zgaga, L et al.. Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis. Hum Mol Genet. 2014;23 (17):4729-37. doi: 10.1093/hmg/ddu177. PubMed PMID:24737748 PubMed Central PMC4133584.
  285. Leventhal, AM, Lee, W, Bergen, AW, Swan, GE, Tyndale, RF, Lerman, C et al.. Nicotine dependence as a moderator of genetic influences on smoking cessation treatment outcome. Drug Alcohol Depend. 2014;138 :109-17. doi: 10.1016/j.drugalcdep.2014.02.016. PubMed PMID:24667010 PubMed Central PMC4095777.
  286. Figueroa, JD, Han, SS, Garcia-Closas, M, Baris, D, Jacobs, EJ, Kogevinas, M et al.. Genome-wide interaction study of smoking and bladder cancer risk. Carcinogenesis. 2014;35 (8):1737-44. doi: 10.1093/carcin/bgu064. PubMed PMID:24662972 PubMed Central PMC4123644.
  287. Ahsan, H, Halpern, J, Kibriya, MG, Pierce, BL, Tong, L, Gamazon, E et al.. A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age. Cancer Epidemiol Biomarkers Prev. 2014;23 (4):658-69. doi: 10.1158/1055-9965.EPI-13-0340. PubMed PMID:24493630 PubMed Central PMC3990360.
  288. Young, B, Conti, DV, Dean, MD. Sneaker "jack" males outcompete dominant "hooknose" males under sperm competition in Chinook salmon (Oncorhynchus tshawytscha). Ecol Evol. 2013;3 (15):4987-97. doi: 10.1002/ece3.869. PubMed PMID:24455130 PubMed Central PMC3892362.
  289. Corral, R, Lewinger, JP, Van Den Berg, D, Joshi, AD, Yuan, JM, Gago-Dominguez, M et al.. Comprehensive analyses of DNA repair pathways, smoking and bladder cancer risk in Los Angeles and Shanghai. Int J Cancer. 2014;135 (2):335-47. doi: 10.1002/ijc.28693. PubMed PMID:24382701 PubMed Central PMC4016180.
  290. Biancolella, M, Fortini, BK, Tring, S, Plummer, SJ, Mendoza-Fandino, GA, Hartiala, J et al.. Identification and characterization of functional risk variants for colorectal cancer mapping to chromosome 11q23.1. Hum Mol Genet. 2014;23 (8):2198-209. doi: 10.1093/hmg/ddt584. PubMed PMID:24256810 PubMed Central PMC3959808.
  291. Davis, LK, Yu, D, Keenan, CL, Gamazon, ER, Konkashbaev, AI, Derks, EM et al.. Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture. PLoS Genet. 2013;9 (10):e1003864. doi: 10.1371/journal.pgen.1003864. PubMed PMID:24204291 PubMed Central PMC3812053.
  292. Figueroa, JD, Ye, Y, Siddiq, A, Garcia-Closas, M, Chatterjee, N, Prokunina-Olsson, L et al.. Genome-wide association study identifies multiple loci associated with bladder cancer risk. Hum Mol Genet. 2014;23 (5):1387-98. doi: 10.1093/hmg/ddt519. PubMed PMID:24163127 PubMed Central PMC3919005.
  293. Baurley, JW, Conti, DV. A scalable, knowledge-based analysis framework for genetic association studies. BMC Bioinformatics. 2013;14 :312. doi: 10.1186/1471-2105-14-312. PubMed PMID:24152222 PubMed Central PMC4015032.
  294. Hiraki, LT, Qu, C, Hutter, CM, Baron, JA, Berndt, SI, Bézieau, S et al.. Genetic predictors of circulating 25-hydroxyvitamin d and risk of colorectal cancer. Cancer Epidemiol Biomarkers Prev. 2013;22 (11):2037-46. doi: 10.1158/1055-9965.EPI-13-0209. PubMed PMID:23983240 PubMed Central PMC3818310.
  295. Siparsky, NF, Al-Rohil, RN, Huho, AN, Ferguson, JR, Graig, JA, Gallichio, MH et al.. Rescue thrombolysis: resolution of intraglomerular thrombi after donation after circulatory death. Transplantation. 2013;96 (4):e31-2. doi: 10.1097/TP.0b013e31829e93f1. PubMed PMID:23958889 .
  296. David, SP, Strong, DR, Leventhal, AM, Lancaster, MA, McGeary, JE, Munafò, MR et al.. Influence of a dopamine pathway additive genetic efficacy score on smoking cessation: results from two randomized clinical trials of bupropion. Addiction. 2013;108 (12):2202-11. doi: 10.1111/add.12325. PubMed PMID:23941313 PubMed Central PMC3834197.
  297. Cheng, I, Kocarnik, JM, Dumitrescu, L, Lindor, NM, Chang-Claude, J, Avery, CL et al.. Pleiotropic effects of genetic risk variants for other cancers on colorectal cancer risk: PAGE, GECCO and CCFR consortia. Gut. 2014;63 (5):800-7. doi: 10.1136/gutjnl-2013-305189. PubMed PMID:23935004 PubMed Central PMC3918490.
  298. Whiffin, N, Dobbins, SE, Hosking, FJ, Palles, C, Tenesa, A, Wang, Y et al.. Deciphering the genetic architecture of low-penetrance susceptibility to colorectal cancer. Hum Mol Genet. 2013;22 (24):5075-82. doi: 10.1093/hmg/ddt357. PubMed PMID:23904454 PubMed Central PMC3836483.
  299. Lewinger, JP, Morrison, JL, Thomas, DC, Murcray, CE, Conti, DV, Li, D et al.. Efficient two-step testing of gene-gene interactions in genome-wide association studies. Genet Epidemiol. 2013;37 (5):440-51. doi: 10.1002/gepi.21720. PubMed PMID:23633124 .
  300. Jiang, X, Castelao, JE, Vandenberg, D, Carracedo, A, Redondo, CM, Conti, DV et al.. Genetic variations in SMAD7 are associated with colorectal cancer risk in the colon cancer family registry. PLoS One. 2013;8 (4):e60464. doi: 10.1371/journal.pone.0060464. PubMed PMID:23560096 PubMed Central PMC3616155.
  301. Tao, L, Day, BW, Hu, B, Xiang, YB, Wang, R, Stern, MC et al.. Elevated 4-aminobiphenyl and 2,6-dimethylaniline hemoglobin adducts and increased risk of bladder cancer among lifelong nonsmokers--The Shanghai Bladder Cancer Study. Cancer Epidemiol Biomarkers Prev. 2013;22 (5):937-45. doi: 10.1158/1055-9965.EPI-12-1447. PubMed PMID:23539508 PubMed Central PMC4065796.
  302. Conti, DJ, Lempert, N, Stain, SC. History of the Department of Surgery at Albany Medical Center. Am Surg. 2013;79 (3):221-31. . PubMed PMID:23461944 .
  303. Li, R, Conti, DV, Diaz-Sanchez, D, Gilliland, F, Thomas, DC. Joint analysis for integrating two related studies of different data types and different study designs using hierarchical modeling approaches. Hum Hered. 2012;74 (2):83-96. doi: 10.1159/000345181. PubMed PMID:23343600 PubMed Central PMC4106669.
  304. Liu, J, Lewinger, JP, Gilliland, FD, Gauderman, WJ, Conti, DV. Confounding and heterogeneity in genetic association studies with admixed populations. Am J Epidemiol. 2013;177 (4):351-60. doi: 10.1093/aje/kws234. PubMed PMID:23334005 PubMed Central PMC3626055.
  305. Jiao, S, Hsu, L, Berndt, S, Bézieau, S, Brenner, H, Buchanan, D et al.. Genome-wide search for gene-gene interactions in colorectal cancer. PLoS One. 2012;7 (12):e52535. doi: 10.1371/journal.pone.0052535. PubMed PMID:23300701 PubMed Central PMC3530500.
  306. Peters, U, Jiao, S, Schumacher, FR, Hutter, CM, Aragaki, AK, Baron, JA et al.. Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis. Gastroenterology. 2013;144 (4):799-807.e24. doi: 10.1053/j.gastro.2012.12.020. PubMed PMID:23266556 PubMed Central PMC3636812.
  307. Jia, WH, Zhang, B, Matsuo, K, Shin, A, Xiang, YB, Jee, SH et al.. Genome-wide association analyses in East Asians identify new susceptibility loci for colorectal cancer. Nat Genet. 2013;45 (2):191-6. doi: 10.1038/ng.2505. PubMed PMID:23263487 PubMed Central PMC3679924.
  308. Bergen, AW, Javitz, HS, Krasnow, R, Nishita, D, Michel, M, Conti, DV et al.. Nicotinic acetylcholine receptor variation and response to smoking cessation therapies. Pharmacogenet Genomics. 2013;23 (2):94-103. doi: 10.1097/FPC.0b013e32835cdabd. PubMed PMID:23249876 PubMed Central PMC3563676.
  309. Bergen, AW, Javitz, HS, Su, L, He, Y, Conti, DV, Benowitz, NL et al.. The DRD4 exon III VNTR, bupropion, and associations with prospective abstinence. Nicotine Tob Res. 2013;15 (7):1190-200. doi: 10.1093/ntr/nts245. PubMed PMID:23212438 PubMed Central PMC3682839.
  310. Myers, RA, Himes, BE, Gignoux, CR, Yang, JJ, Gauderman, WJ, Rebordosa, C et al.. Further replication studies of the EVE Consortium meta-analysis identifies 2 asthma risk loci in European Americans. J Allergy Clin Immunol. 2012;130 (6):1294-301. doi: 10.1016/j.jaci.2012.07.054. PubMed PMID:23040885 PubMed Central PMC3666859.
  311. Liang, WE, Thomas, DC, Conti, DV. Analysis and optimal design for association studies using next-generation sequencing with case-control pools. Genet Epidemiol. 2012;36 (8):870-81. doi: 10.1002/gepi.21681. PubMed PMID:22972696 PubMed Central PMC4139478.
  312. Frasco, MA, Mack, WJ, Van Den Berg, D, Aouizerat, BE, Anastos, K, Cohen, M et al.. Underlying genetic structure impacts the association between CYP2B6 polymorphisms and response to efavirenz and nevirapine. AIDS. 2012;26 (16):2097-106. doi: 10.1097/QAD.0b013e3283593602. PubMed PMID:22951632 PubMed Central PMC3940150.
  313. Jia, P, Wang, L, Fanous, AH, Pato, CN, Edwards, TL, International Schizophrenia Consortium et al.. Network-assisted investigation of combined causal signals from genome-wide association studies in schizophrenia. PLoS Comput Biol. 2012;8 (7):e1002587. doi: 10.1371/journal.pcbi.1002587. PubMed PMID:22792057 PubMed Central PMC3390381.
  314. Yang, J, Dolinger, M, Ritaccio, G, Mazurkiewicz, J, Conti, D, Zhu, X et al.. Leucine stimulates insulin secretion via down-regulation of surface expression of adrenergic α2A receptor through the mTOR (mammalian target of rapamycin) pathway: implication in new-onset diabetes in renal transplantation. J Biol Chem. 2012;287 (29):24795-806. doi: 10.1074/jbc.M112.344259. PubMed PMID:22645144 PubMed Central PMC3397906.
  315. Dunlop, MG, Dobbins, SE, Farrington, SM, Jones, AM, Palles, C, Whiffin, N et al.. Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk. Nat Genet. 2012;44 (7):770-6. doi: 10.1038/ng.2293. PubMed PMID:22634755 PubMed Central PMC4747430.
  316. Amezcua, L, Chung, RH, Conti, DV, Langer-Gould, AM. Vitamin D levels in Hispanics with multiple sclerosis. J Neurol. 2012;259 (12):2565-70. doi: 10.1007/s00415-012-6537-z. PubMed PMID:22588255 .
  317. Casey, G, Conti, D, Haile, R, Duggan, D. Next generation sequencing and a new era of medicine. Gut. 2013;62 (6):920-32. doi: 10.1136/gutjnl-2011-301935. PubMed PMID:22550129 PubMed Central PMC5105595.
  318. Lee, W, Ray, R, Bergen, AW, Swan, GE, Thomas, P, Tyndale, RF et al.. DRD1 associations with smoking abstinence across slow and normal nicotine metabolizers. Pharmacogenet Genomics. 2012;22 (7):551-4. doi: 10.1097/FPC.0b013e3283539062. PubMed PMID:22495174 PubMed Central PMC3376177.
  319. Gold, AB, Wileyto, EP, Lori, A, Conti, D, Cubells, JF, Lerman, C et al.. Pharmacogenetic association of the galanin receptor (GALR1) SNP rs2717162 with smoking cessation. Neuropsychopharmacology. 2012;37 (7):1683-8. doi: 10.1038/npp.2012.13. PubMed PMID:22373943 PubMed Central PMC3358736.
  320. Quintana, MA, Schumacher, FR, Casey, G, Bernstein, JL, Li, L, Conti, DV et al.. Incorporating prior biologic information for high-dimensional rare variant association studies. Hum Hered. 2012;74 (3-4):184-95. doi: 10.1159/000346021. PubMed PMID:23594496 PubMed Central PMC4058572.
  321. Jia, P, Wang, L, Fanous, AH, Chen, X, Kendler, KS, International Schizophrenia Consortium et al.. A bias-reducing pathway enrichment analysis of genome-wide association data confirmed association of the MHC region with schizophrenia. J Med Genet. 2012;49 (2):96-103. doi: 10.1136/jmedgenet-2011-100397. PubMed PMID:22187495 .
  322. Brisbin, AG, Asmann, YW, Song, H, Tsai, YY, Aakre, JA, Yang, P et al.. Meta-analysis of 8q24 for seven cancers reveals a locus between NOV and ENPP2 associated with cancer development. BMC Med Genet. 2011;12 :156. doi: 10.1186/1471-2350-12-156. PubMed PMID:22142333 PubMed Central PMC3267702.
  323. Cozen, W, Li, D, Best, T, Van Den Berg, DJ, Gourraud, PA, Cortessis, VK et al.. A genome-wide meta-analysis of nodular sclerosing Hodgkin lymphoma identifies risk loci at 6p21.32. Blood. 2012;119 (2):469-75. doi: 10.1182/blood-2011-03-343921. PubMed PMID:22086417 PubMed Central PMC3257012.
  324. King, DP, Paciga, S, Pickering, E, Benowitz, NL, Bierut, LJ, Conti, DV et al.. Smoking cessation pharmacogenetics: analysis of varenicline and bupropion in placebo-controlled clinical trials. Neuropsychopharmacology. 2012;37 (3):641-50. doi: 10.1038/npp.2011.232. PubMed PMID:22048466 PubMed Central PMC3260990.
  325. Quintana, MA, Berstein, JL, Thomas, DC, Conti, DV. Incorporating model uncertainty in detecting rare variants: the Bayesian risk index. Genet Epidemiol. 2011;35 (7):638-49. doi: 10.1002/gepi.20613. PubMed PMID:22009789 PubMed Central PMC3936341.
  326. Li, D, Lewinger, JP, Gauderman, WJ, Murcray, CE, Conti, D. Using extreme phenotype sampling to identify the rare causal variants of quantitative traits in association studies. Genet Epidemiol. 2011;35 (8):790-9. doi: 10.1002/gepi.20628. PubMed PMID:21922541 PubMed Central PMC4238184.
  327. Torgerson, DG, Ampleford, EJ, Chiu, GY, Gauderman, WJ, Gignoux, CR, Graves, PE et al.. Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. Nat Genet. 2011;43 (9):887-92. doi: 10.1038/ng.888. PubMed PMID:21804549 PubMed Central PMC3445408.
  328. Best, T, Li, D, Skol, AD, Kirchhoff, T, Jackson, SA, Yasui, Y et al.. Variants at 6q21 implicate PRDM1 in the etiology of therapy-induced second malignancies after Hodgkin's lymphoma. Nat Med. 2011;17 (8):941-3. doi: 10.1038/nm.2407. PubMed PMID:21785431 PubMed Central PMC3229923.
  329. Peters, U, Hutter, CM, Hsu, L, Schumacher, FR, Conti, DV, Carlson, CS et al.. Meta-analysis of new genome-wide association studies of colorectal cancer risk. Hum Genet. 2012;131 (2):217-34. doi: 10.1007/s00439-011-1055-0. PubMed PMID:21761138 PubMed Central PMC3257356.
  330. Chen, J, Lee, G, Fanous, AH, Zhao, Z, Jia, P, O'Neill, A et al.. Two non-synonymous markers in PTPN21, identified by genome-wide association study data-mining and replication, are associated with schizophrenia. Schizophr Res. 2011;131 (1-3):43-51. doi: 10.1016/j.schres.2011.06.023. PubMed PMID:21752600 PubMed Central PMC4117700.
  331. Tomlinson, IP, Carvajal-Carmona, LG, Dobbins, SE, Tenesa, A, Jones, AM, Howarth, K et al.. Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer. PLoS Genet. 2011;7 (6):e1002105. doi: 10.1371/journal.pgen.1002105. PubMed PMID:21655089 PubMed Central PMC3107194.
  332. Bridges, M, Heron, EA, O'Dushlaine, C, Segurado, R, International Schizophrenia Consortium (ISC), Morris, D et al.. Genetic classification of populations using supervised learning. PLoS One. 2011;6 (5):e14802. doi: 10.1371/journal.pone.0014802. PubMed PMID:21589856 PubMed Central PMC3093382.
  333. Carvajal-Carmona, LG, Cazier, JB, Jones, AM, Howarth, K, Broderick, P, Pittman, A et al.. Fine-mapping of colorectal cancer susceptibility loci at 8q23.3, 16q22.1 and 19q13.11: refinement of association signals and use of in silico analysis to suggest functional variation and unexpected candidate target genes. Hum Mol Genet. 2011;20 (14):2879-88. doi: 10.1093/hmg/ddr190. PubMed PMID:21531788 PubMed Central PMC3118761.
  334. Davis-Dao, CA, Henderson, KD, Sullivan-Halley, J, Ma, H, West, D, Xiang, YB et al.. Lower risk in parous women suggests that hormonal factors are important in bladder cancer etiology. Cancer Epidemiol Biomarkers Prev. 2011;20 (6):1156-70. doi: 10.1158/1055-9965.EPI-11-0017. PubMed PMID:21493870 PubMed Central PMC3312020.
  335. Patino, CM, Varma, R, Azen, SP, Conti, DV, Nichol, MB, McKean-Cowdin, R et al.. The impact of change in visual field on health-related quality of life the los angeles latino eye study. Ophthalmology. 2011;118 (7):1310-7. doi: 10.1016/j.ophtha.2010.12.018. PubMed PMID:21458074 PubMed Central PMC3129408.
  336. Pearce, CL, Doherty, JA, Van Den Berg, DJ, Moysich, K, Hsu, C, Cushing-Haugen, KL et al.. Genetic variation in insulin-like growth factor 2 may play a role in ovarian cancer risk. Hum Mol Genet. 2011;20 (11):2263-72. doi: 10.1093/hmg/ddr087. PubMed PMID:21422097 PubMed Central PMC3090188.
  337. Li, D, London, SJ, Liu, J, Lee, W, Jiang, X, Van Den Berg, D et al.. Association of the calcyon neuron-specific vesicular protein gene (CALY) with adolescent smoking initiation in China and California. Am J Epidemiol. 2011;173 (9):1039-48. doi: 10.1093/aje/kwq471. PubMed PMID:21415033 PubMed Central PMC3121219.
  338. Jiang, X, Castelao, JE, Yuan, JM, Stern, MC, Conti, DV, Cortessis, VK et al.. Cigarette smoking and subtypes of bladder cancer. Int J Cancer. 2012;130 (4):896-901. doi: 10.1002/ijc.26068. PubMed PMID:21412765 PubMed Central PMC3210924.
  339. Figueiredo, JC, Lewinger, JP, Song, C, Campbell, PT, Conti, DV, Edlund, CK et al.. Genotype-environment interactions in microsatellite stable/microsatellite instability-low colorectal cancer: results from a genome-wide association study. Cancer Epidemiol Biomarkers Prev. 2011;20 (5):758-66. doi: 10.1158/1055-9965.EPI-10-0675. PubMed PMID:21357381 PubMed Central PMC3089660.
  340. Richards, AL, Jones, L, Moskvina, V, Kirov, G, Gejman, PV, Levinson, DF et al.. Schizophrenia susceptibility alleles are enriched for alleles that affect gene expression in adult human brain. Mol Psychiatry. 2012;17 (2):193-201. doi: 10.1038/mp.2011.11. PubMed PMID:21339752 PubMed Central PMC4761872.
  341. Murcray, CE, Lewinger, JP, Conti, DV, Thomas, DC, Gauderman, WJ. Sample size requirements to detect gene-environment interactions in genome-wide association studies. Genet Epidemiol. 2011;35 (3):201-10. doi: 10.1002/gepi.20569. PubMed PMID:21308767 PubMed Central PMC3076801.
  342. Hartiala, J, Li, D, Conti, DV, Vikman, S, Patel, Y, Tang, WH et al.. Genetic contribution of the leukotriene pathway to coronary artery disease. Hum Genet. 2011;129 (6):617-27. doi: 10.1007/s00439-011-0963-3. PubMed PMID:21293878 PubMed Central PMC3092945.
  343. Levine, AJ, Lee, W, Figueiredo, JC, Conti, DV, Vandenberg, DJ, Davis, BD et al.. Variation in folate pathway genes and distal colorectal adenoma risk: a sigmoidoscopy-based case-control study. Cancer Causes Control. 2011;22 (4):541-52. doi: 10.1007/s10552-011-9726-7. PubMed PMID:21274745 PubMed Central PMC3059778.
  344. Figueiredo, JC, Brooks, JD, Conti, DV, Poynter, JN, Teraoka, SN, Malone, KE et al.. Risk of contralateral breast cancer associated with common variants in BRCA1 and BRCA2: potential modifying effect of BRCA1/BRCA2 mutation carrier status. Breast Cancer Res Treat. 2011;127 (3):819-29. doi: 10.1007/s10549-010-1285-1. PubMed PMID:21161372 PubMed Central PMC3234998.
  345. Gago-Dominguez, M, Jiang, X, Conti, DV, Castelao, JE, Stern, MC, Cortessis, VK et al.. Genetic variations on chromosomes 5p15 and 15q25 and bladder cancer risk: findings from the Los Angeles-Shanghai bladder case-control study. Carcinogenesis. 2011;32 (2):197-202. doi: 10.1093/carcin/bgq233. PubMed PMID:21081471 PubMed Central PMC3026841.
  346. Thomas, DC, Conti, DV, Baurley, J, Nijhout, F, Reed, M, Ulrich, CM et al.. Use of pathway information in molecular epidemiology. Hum Genomics. 2009;4 (1):21-42. doi: 10.1186/1479-7364-4-1-21. PubMed PMID:21072972 PubMed Central PMC2999471.
  347. Cortessis, VK, Yuan, JM, Van Den Berg, D, Jiang, X, Gago-Dominguez, M, Stern, MC et al.. Risk of urinary bladder cancer is associated with 8q24 variant rs9642880[T] in multiple racial/ethnic groups: results from the Los Angeles-Shanghai case-control study. Cancer Epidemiol Biomarkers Prev. 2010;19 (12):3150-6. doi: 10.1158/1055-9965.EPI-10-0763. PubMed PMID:21051319 PubMed Central PMC3417222.
  348. Wilson, MA, Baurley, JW, Thomas, DC, Conti, DV. Complex system approaches to genetic analysis Bayesian approaches. Adv Genet. 2010;72 :47-71. doi: 10.1016/B978-0-12-380862-2.00003-5. PubMed PMID:21029848 PubMed Central PMC4190044.
  349. Alderete, TL, Byrd-Williams, CE, Toledo-Corral, CM, Conti, DV, Weigensberg, MJ, Goran, MI et al.. Relationships between IGF-1 and IGFBP-1 and adiposity in obese African-American and Latino adolescents. Obesity (Silver Spring). 2011;19 (5):933-8. doi: 10.1038/oby.2010.211. PubMed PMID:20885383 PubMed Central PMC3081365.
  350. Raychaudhuri, S, Korn, JM, McCarroll, SA, International Schizophrenia Consortium, Altshuler, D, Sklar, P et al.. Accurately assessing the risk of schizophrenia conferred by rare copy-number variation affecting genes with brain function. PLoS Genet. 2010;6 (9):e1001097. doi: 10.1371/journal.pgen.1001097. PubMed PMID:20838587 PubMed Central PMC2936523.
  351. Chen, X, Lee, G, Maher, BS, Fanous, AH, Chen, J, Zhao, Z et al.. GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia. Mol Psychiatry. 2011;16 (11):1117-29. doi: 10.1038/mp.2010.96. PubMed PMID:20838396 PubMed Central PMC3443634.
  352. Jiang, X, Castelao, JE, Yuan, JM, Groshen, S, Stern, MC, Conti, DV et al.. Hypertension, diuretics and antihypertensives in relation to bladder cancer. Carcinogenesis. 2010;31 (11):1964-71. doi: 10.1093/carcin/bgq173. PubMed PMID:20732908 PubMed Central PMC2966553.
  353. Baurley, JW, Conti, DV, Gauderman, WJ, Thomas, DC. Discovery of complex pathways from observational data. Stat Med. 2010;29 (19):1998-2011. doi: 10.1002/sim.3962. PubMed PMID:20683892 PubMed Central PMC2922970.
  354. Levine, AJ, Figueiredo, JC, Lee, W, Conti, DV, Kennedy, K, Duggan, DJ et al.. A candidate gene study of folate-associated one carbon metabolism genes and colorectal cancer risk. Cancer Epidemiol Biomarkers Prev. 2010;19 (7):1812-21. doi: 10.1158/1055-9965.EPI-10-0151. PubMed PMID:20615890 PubMed Central PMC2950115.
  355. Thomas, DC, Casey, G, Conti, DV, Haile, RW, Lewinger, JP, Stram, DO et al.. Methodological Issues in Multistage Genome-wide Association Studies. Stat Sci. 2009;24 (4):414-429. doi: 10.1214/09-sts288. PubMed PMID:20607129 PubMed Central PMC2895324.
  356. Jacobs, ET, Martínez, ME, Campbell, PT, Conti, DV, Duggan, D, Figueiredo, JC et al.. Genetic variation in the retinoid X receptor and calcium-sensing receptor and risk of colorectal cancer in the Colon Cancer Family Registry. Carcinogenesis. 2010;31 (8):1412-6. doi: 10.1093/carcin/bgq127. PubMed PMID:20558521 PubMed Central PMC2915636.
  357. Gauderman, WJ, Thomas, DC, Murcray, CE, Conti, D, Li, D, Lewinger, JP et al.. Efficient genome-wide association testing of gene-environment interaction in case-parent trios. Am J Epidemiol. 2010;172 (1):116-22. doi: 10.1093/aje/kwq097. PubMed PMID:20543031 PubMed Central PMC2915477.
  358. Unger, JB, Lessov-Schlaggar, CN, Pang, Z, Guo, Q, Ning, F, Gallaher, P et al.. Heritability of smoking, alcohol use, and psychological characteristics among adolescent twins in Qingdao, China. Asia Pac J Public Health. 2011;23 (4):568-80. doi: 10.1177/1010539509351052. PubMed PMID:20484245 PubMed Central PMC4406051.
  359. O'Dushlaine, C, Kenny, E, Heron, E, Donohoe, G, Gill, M, Morris, D et al.. Molecular pathways involved in neuronal cell adhesion and membrane scaffolding contribute to schizophrenia and bipolar disorder susceptibility. Mol Psychiatry. 2011;16 (3):286-92. doi: 10.1038/mp.2010.7. PubMed PMID:20157312 .
  360. Egan, JB, Thompson, PA, Ashbeck, EL, Conti, DV, Duggan, D, Hibler, E et al.. Genetic polymorphisms in vitamin D receptor VDR/RXRA influence the likelihood of colon adenoma recurrence. Cancer Res. 2010;70 (4):1496-504. doi: 10.1158/0008-5472.CAN-09-3264. PubMed PMID:20145122 PubMed Central PMC3019606.
  361. Poynter, JN, Jacobs, ET, Figueiredo, JC, Lee, WH, Conti, DV, Campbell, PT et al.. Genetic variation in the vitamin D receptor (VDR) and the vitamin D-binding protein (GC) and risk for colorectal cancer: results from the Colon Cancer Family Registry. Cancer Epidemiol Biomarkers Prev. 2010;19 (2):525-36. doi: 10.1158/1055-9965.EPI-09-0662. PubMed PMID:20086113 PubMed Central PMC2819604.
  362. Gebregziabher, M, Guimaraes, P, Cozen, W, Conti, DV. A polytomous conditional likelihood approach for combining matched and unmatched case-control studies. Stat Med. 2010;29 (9):1004-13. doi: 10.1002/sim.3833. PubMed PMID:20069625 PubMed Central PMC2889167.
  363. Levine, AJ, Figueiredo, JC, Lee, W, Poynter, JN, Conti, D, Duggan, DJ et al.. Genetic variability in the MTHFR gene and colorectal cancer risk using the colorectal cancer family registry. Cancer Epidemiol Biomarkers Prev. 2010;19 (1):89-100. doi: 10.1158/1055-9965.EPI-09-0727. PubMed PMID:20056627 PubMed Central PMC2805460.
  364. Figueiredo, JC, Levine, AJ, Lee, WH, Conti, DV, Poynter, JN, Campbell, PT et al.. Genes involved with folate uptake and distribution and their association with colorectal cancer risk. Cancer Causes Control. 2010;21 (4):597-608. doi: 10.1007/s10552-009-9489-6. PubMed PMID:20037791 PubMed Central PMC2904058.
  365. Islam, T, Breton, C, Salam, MT, McConnell, R, Wenten, M, Gauderman, WJ et al.. Role of inducible nitric oxide synthase in asthma risk and lung function growth during adolescence. Thorax. 2010;65 (2):139-45. doi: 10.1136/thx.2009.114355. PubMed PMID:19996333 .
  366. Gordon, EJ, Prohaska, TR, Gallant, MP, Sehgal, AR, Strogatz, D, Conti, D et al.. Prevalence and determinants of physical activity and fluid intake in kidney transplant recipients. Clin Transplant. 2010;24 (3):E69-81. doi: 10.1111/j.1399-0012.2009.01154.x. PubMed PMID:19925468 PubMed Central PMC2925539.
  367. Tilney, N, Murray, J, Thistlethwaite, R, Norman, D, Delmonico, F, Hanto, D et al.. Promotion of altruistic donation. Transplantation. 2009;88 (6):847. doi: 10.1097/TP.0b013e3181b6bd65. PubMed PMID:19920786 .
  368. Shtir, CJ, Marjoram, P, Azen, S, Conti, DV, Le Marchand, L, Haiman, CA et al.. Variation in genetic admixture and population structure among Latinos: the Los Angeles Latino eye study (LALES). BMC Genet. 2009;10 :71. doi: 10.1186/1471-2156-10-71. PubMed PMID:19903357 PubMed Central PMC3087512.
  369. Stern, MC, Van Den Berg, D, Yuan, JM, Conti, DV, Gago-Dominguez, M, Pike, MC et al.. Sequence variant on 3q28 and urinary bladder cancer risk: findings from the Los Angeles-Shanghai bladder case-control study. Cancer Epidemiol Biomarkers Prev. 2009;18 (11):3057-61. doi: 10.1158/1055-9965.EPI-09-0492. PubMed PMID:19843673 PubMed Central PMC2783174.
  370. Gordon, EJ, Prohaska, TR, Gallant, MP, Sehgal, AR, Strogatz, D, Yucel, R et al.. Longitudinal analysis of physical activity, fluid intake, and graft function among kidney transplant recipients. Transpl Int. 2009;22 (10):990-8. doi: 10.1111/j.1432-2277.2009.00917.x. PubMed PMID:19619168 PubMed Central PMC2925536.
  371. International Schizophrenia Consortium, Purcell, SM, Wray, NR, Stone, JL, Visscher, PM, O'Donovan, MC et al.. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature. 2009;460 (7256):748-52. doi: 10.1038/nature08185. PubMed PMID:19571811 PubMed Central PMC3912837.
  372. Khemani, RG, Conti, D, Alonzo, TA, Bart, RD 3rd, Newth, CJ. Effect of tidal volume in children with acute hypoxemic respiratory failure. Intensive Care Med. 2009;35 (8):1428-37. doi: 10.1007/s00134-009-1527-z. PubMed PMID:19533092 .
  373. Thomas, PD, Mi, H, Swan, GE, Lerman, C, Benowitz, N, Tyndale, RF et al.. A systems biology network model for genetic association studies of nicotine addiction and treatment. Pharmacogenet Genomics. 2009;19 (7):538-51. doi: 10.1097/FPC.0b013e32832e2ced. PubMed PMID:19525886 PubMed Central PMC6485245.
  374. Bergen, AW, Conti, DV, Van Den Berg, D, Lee, W, Liu, J, Li, D et al.. Dopamine genes and nicotine dependence in treatment-seeking and community smokers. Neuropsychopharmacology. 2009;34 (10):2252-64. doi: 10.1038/npp.2009.52. PubMed PMID:19494806 PubMed Central PMC3558036.
  375. Petrov, R, Elbahloul, O, Gallichio, MH, Stellrecht, K, Conti, DJ. Monthly screening for polyoma virus eliminates BK nephropathy and preserves renal function. Surg Infect (Larchmt). 2009;10 (1):85-90. doi: 10.1089/sur.2008.052. PubMed PMID:19298172 .
  376. Schildkraut, JM, Goode, EL, Clyde, MA, Iversen, ES, Moorman, PG, Berchuck, A et al.. Single nucleotide polymorphisms in the TP53 region and susceptibility to invasive epithelial ovarian cancer. Cancer Res. 2009;69 (6):2349-57. doi: 10.1158/0008-5472.CAN-08-2902. PubMed PMID:19276375 PubMed Central PMC2666150.
  377. Chang, ET, Birmann, BM, Kasperzyk, JL, Conti, DV, Kraft, P, Ambinder, RF et al.. Polymorphic variation in NFKB1 and other aspirin-related genes and risk of Hodgkin lymphoma. Cancer Epidemiol Biomarkers Prev. 2009;18 (3):976-86. doi: 10.1158/1055-9965.EPI-08-1130. PubMed PMID:19223558 PubMed Central PMC2720066.
  378. Srinivasan, BS, Chen, J, Cheng, C, Conti, D, Duan, S, Fridley, BL et al.. Methods for analysis in pharmacogenomics: lessons from the Pharmacogenetics Research Network Analysis Group. Pharmacogenomics. 2009;10 (2):243-51. doi: 10.2217/14622416.10.2.243. PubMed PMID:19207025 PubMed Central PMC2737060.
  379. Gordon, EJ, Gallant, M, Sehgal, AR, Conti, D, Siminoff, LA. Medication-taking among adult renal transplant recipients: barriers and strategies. Transpl Int. 2009;22 (5):534-45. doi: 10.1111/j.1432-2277.2008.00827.x. PubMed PMID:19175560 PubMed Central PMC3540791.
  380. Li, D, Conti, DV. Detecting gene-environment interactions using a combined case-only and case-control approach. Am J Epidemiol. 2009;169 (4):497-504. doi: 10.1093/aje/kwn339. PubMed PMID:19074774 PubMed Central PMC2732970.
  381. Bostom, AG, Carpenter, MA, Hunsicker, L, Jacques, PF, Kusek, JW, Levey, AS et al.. Baseline characteristics of participants in the Folic Acid for Vascular Outcome Reduction in Transplantation (FAVORIT) Trial. Am J Kidney Dis. 2009;53 (1):121-8. doi: 10.1053/j.ajkd.2008.08.010. PubMed PMID:19022547 PubMed Central PMC2682551.
  382. Conti, DJ, Petrov, R, Elbalhoul, O, Gallichio, M. Sirolimus-based, calcineurin-inhibitor sparing immunotherapy, long-term (6-year) results. Transpl Immunol. 2008;20 (1-2):12-3. doi: 10.1016/j.trim.2008.08.011. PubMed PMID:18793727 .
  383. Transdisciplinary Tobacco Use Research Center (TTURC) Tobacco Dependence, Baker, TB, Piper, ME, McCarthy, DE, Bolt, DM, Smith, SS et al.. Time to first cigarette in the morning as an index of ability to quit smoking: implications for nicotine dependence. Nicotine Tob Res. 2007;9 Suppl 4 (Suppl 4):S555-70. doi: 10.1080/14622200701673480. PubMed PMID:18067032 PubMed Central PMC2933747.
  384. International Schizophrenia Consortium. Rare chromosomal deletions and duplications increase risk of schizophrenia. Nature. 2008;455 (7210):237-41. doi: 10.1038/nature07239. PubMed PMID:18668038 PubMed Central PMC3912847.
  385. Jiang, X, Castelao, JE, Groshen, S, Cortessis, VK, Shibata, DK, Conti, DV et al.. Water intake and bladder cancer risk in Los Angeles County. Int J Cancer. 2008;123 (7):1649-56. doi: 10.1002/ijc.23711. PubMed PMID:18623082 .
  386. Conti, DV, Lee, W, Li, D, Liu, J, Van Den Berg, D, Thomas, PD et al.. Nicotinic acetylcholine receptor beta2 subunit gene implicated in a systems-based candidate gene study of smoking cessation. Hum Mol Genet. 2008;17 (18):2834-48. doi: 10.1093/hmg/ddn181. PubMed PMID:18593715 PubMed Central PMC2525499.
  387. Shihab, FS, Waid, TH, Conti, DJ, Yang, H, Holman, MJ, Mulloy, LC et al.. Conversion from cyclosporine to tacrolimus in patients at risk for chronic renal allograft failure: 60-month results of the CRAF Study. Transplantation. 2008;85 (9):1261-9. doi: 10.1097/TP.0b013e31816b4388. PubMed PMID:18475181 .
  388. Edlund, CK, Lee, WH, Li, D, Van Den Berg, DJ, Conti, DV. Snagger: a user-friendly program for incorporating additional information for tagSNP selection. BMC Bioinformatics. 2008;9 :174. doi: 10.1186/1471-2105-9-174. PubMed PMID:18371222 PubMed Central PMC2375134.
  389. Li, YF, Gauderman, WJ, Conti, DV, Lin, PC, Avol, E, Gilliland, FD et al.. Glutathione S-transferase P1, maternal smoking, and asthma in children: a haplotype-based analysis. Environ Health Perspect. 2008;116 (3):409-15. doi: 10.1289/ehp.10655. PubMed PMID:18335111 PubMed Central PMC2265034.
  390. Leigh Pearce, C, Near, AM, Butler, JL, Van Den Berg, D, Bretsky, P, Conti, DV et al.. Comprehensive evaluation of ESR2 variation and ovarian cancer risk. Cancer Epidemiol Biomarkers Prev. 2008;17 (2):393-6. doi: 10.1158/1055-9965.EPI-07-2512. PubMed PMID:18268123 .
  391. Pemberton, TJ, Mehta, NU, Witonsky, D, Di Rienzo, A, Allayee, H, Conti, DV et al.. Prevalence of common disease-associated variants in Asian Indians. BMC Genet. 2008;9 :13. doi: 10.1186/1471-2156-9-13. PubMed PMID:18248681 PubMed Central PMC2267478.
  392. Poynter, JN, Figueiredo, JC, Conti, DV, Kennedy, K, Gallinger, S, Siegmund, KD et al.. Variants on 9p24 and 8q24 are associated with risk of colorectal cancer: results from the Colon Cancer Family Registry. Cancer Res. 2007;67 (23):11128-32. doi: 10.1158/0008-5472.CAN-07-3239. PubMed PMID:18056436 .
  393. Stern, MC, Conti, DV, Siegmund, KD, Corral, R, Yuan, JM, Koh, WP et al.. DNA repair single-nucleotide polymorphisms in colorectal cancer and their role as modifiers of the effect of cigarette smoking and alcohol in the Singapore Chinese Health Study. Cancer Epidemiol Biomarkers Prev. 2007;16 (11):2363-72. doi: 10.1158/1055-9965.EPI-07-0268. PubMed PMID:18006925 .
  394. Lewinger, JP, Conti, DV, Baurley, JW, Triche, TJ, Thomas, DC. Hierarchical Bayes prioritization of marker associations from a genome-wide association scan for further investigation. Genet Epidemiol. 2007;31 (8):871-82. doi: 10.1002/gepi.20248. PubMed PMID:17654612 .
  395. Allayee, H, Hartiala, J, Lee, W, Mehrabian, M, Irvin, CG, Conti, DV et al.. The effect of montelukast and low-dose theophylline on cardiovascular disease risk factors in asthmatics. Chest. 2007;132 (3):868-74. doi: 10.1378/chest.07-0831. PubMed PMID:17646220 .
  396. Jiang, X, Castelao, JE, Groshen, S, Cortessis, VK, Ross, RK, Conti, DV et al.. Alcohol consumption and risk of bladder cancer in Los Angeles County. Int J Cancer. 2007;121 (4):839-45. doi: 10.1002/ijc.22743. PubMed PMID:17440923 .
  397. Gauderman, WJ, Murcray, C, Gilliland, F, Conti, DV. Testing association between disease and multiple SNPs in a candidate gene. Genet Epidemiol. 2007;31 (5):383-95. doi: 10.1002/gepi.20219. PubMed PMID:17410554 .
  398. Jaber, JJ, Feustel, PJ, Elbahloul, O, Conti, AD, Gallichio, MH, Conti, DJ et al.. Early steroid withdrawal therapy in renal transplant recipients: a steroid-free sirolimus and CellCept-based calcineurin inhibitor-minimization protocol. Clin Transplant. 2007;21 (1):101-9. doi: 10.1111/j.1399-0012.2006.00613.x. PubMed PMID:17302598 .
  399. Stern, MC, Siegmund, KD, Conti, DV, Corral, R, Haile, RW. XRCC1, XRCC3, and XPD polymorphisms as modifiers of the effect of smoking and alcohol on colorectal adenoma risk. Cancer Epidemiol Biomarkers Prev. 2006;15 (12):2384-90. doi: 10.1158/1055-9965.EPI-06-0381. PubMed PMID:17164360 .
  400. Cozen, W, Gebregziabher, M, Conti, DV, Van Den Berg, DJ, Coetzee, GA, Wang, SS et al.. Interleukin-6-related genotypes, body mass index, and risk of multiple myeloma and plasmacytoma. Cancer Epidemiol Biomarkers Prev. 2006;15 (11):2285-91. doi: 10.1158/1055-9965.EPI-06-0446. PubMed PMID:17119059 .
  401. Sun, W, Andreeva, VA, Unger, JB, Conti, DV, Chou, CP, Palmer, PH et al.. Age-related smoking progression among adolescents in China. J Adolesc Health. 2006;39 (5):686-93. doi: 10.1016/j.jadohealth.2006.04.023. PubMed PMID:17046505 .
  402. Millstein, J, Siegmund, KD, Conti, DV, Gauderman, WJ. Identifying susceptibility genes by using joint tests of association and linkage and accounting for epistasis. BMC Genet. 2005;6 Suppl 1 (Suppl 1):S147. doi: 10.1186/1471-2156-6-S1-S147. PubMed PMID:16451607 PubMed Central PMC1866788.
  403. Millstein, J, Conti, DV, Gilliland, FD, Gauderman, WJ. A testing framework for identifying susceptibility genes in the presence of epistasis. Am J Hum Genet. 2006;78 (1):15-27. doi: 10.1086/498850. PubMed PMID:16385446 PubMed Central PMC1380213.
  404. Millstein, J, Siegmund, KD, Conti, DV, Gauderman, WJ. Testing association and linkage using affected-sib-parent study designs. Genet Epidemiol. 2005;29 (3):225-33. doi: 10.1002/gepi.20091. PubMed PMID:16121357 .
  405. Li, YF, Tsao, YH, Gauderman, WJ, Conti, DV, Avol, E, Dubeau, L et al.. Intercellular adhesion molecule-1 and childhood asthma. Hum Genet. 2005;117 (5):476-84. doi: 10.1007/s00439-005-1319-7. PubMed PMID:16021473 .
  406. Haiman, CA, Riley, SE, Freedman, ML, Setiawan, VW, Conti, DV, Le Marchand, L et al.. Common genetic variation in the sex steroid hormone-binding globulin (SHBG) gene and circulating shbg levels among postmenopausal women: the Multiethnic Cohort. J Clin Endocrinol Metab. 2005;90 (4):2198-204. doi: 10.1210/jc.2004-1417. PubMed PMID:15634719 .
  407. Molitor, J, Marjoram, P, Conti, D, Thomas, D. A survey of current Bayesian gene mapping methods. Hum Genomics. 2004;1 (5):371-4. doi: 10.1186/1479-7364-1-5-371. PubMed PMID:15588497 PubMed Central PMC3525098.
  408. Conti, DV, Gauderman, WJ. SNPs, haplotypes, and model selection in a candidate gene region: the SIMPle analysis for multilocus data. Genet Epidemiol. 2004;27 (4):429-41. doi: 10.1002/gepi.20039. PubMed PMID:15543635 .
  409. Cicek, MS, Nock, NL, Li, L, Conti, DV, Casey, G, Witte, JS et al.. Relationship between methylenetetrahydrofolate reductase C677T and A1298C genotypes and haplotypes and prostate cancer risk and aggressiveness. Cancer Epidemiol Biomarkers Prev. 2004;13 (8):1331-6. . PubMed PMID:15298954 .
  410. Thomas, DC, Conti, DV. Commentary: the concept of 'Mendelian Randomization'. Int J Epidemiol. 2004;33 (1):21-5. doi: 10.1093/ije/dyh048. PubMed PMID:15075141 .
  411. Singer, JB, Hill, AE, Burrage, LC, Olszens, KR, Song, J, Justice, M et al.. Genetic dissection of complex traits with chromosome substitution strains of mice. Science. 2004;304 (5669):445-8. doi: 10.1126/science.1093139. PubMed PMID:15031436 .
  412. Cicek, MS, Conti, DV, Curran, A, Neville, PJ, Paris, PL, Casey, G et al.. Association of prostate cancer risk and aggressiveness to androgen pathway genes: SRD5A2, CYP17, and the AR. Prostate. 2004;59 (1):69-76. doi: 10.1002/pros.10358. PubMed PMID:14991867 .
  413. Xing, C, Schumacher, FR, Conti, DV, Witte, JS. Comparison of missing data approaches in linkage analysis. BMC Genet. 2003;4 Suppl 1 (Suppl 1):S44. doi: 10.1186/1471-2156-4-S1-S44. PubMed PMID:14975112 PubMed Central PMC1866480.
  414. Rybicki, BA, Conti, DV, Moreira, A, Cicek, M, Casey, G, Witte, JS et al.. DNA repair gene XRCC1 and XPD polymorphisms and risk of prostate cancer. Cancer Epidemiol Biomarkers Prev. 2004;13 (1):23-9. doi: 10.1158/1055-9965.epi-03-0053. PubMed PMID:14744728 .
  415. Conti, DV, Cortessis, V, Molitor, J, Thomas, DC. Bayesian modeling of complex metabolic pathways. Hum Hered. 2003;56 (1-3):83-93. doi: 10.1159/000073736. PubMed PMID:14614242 .
  416. Thomas, DC, Stram, DO, Conti, D, Molitor, J, Marjoram, P. Bayesian spatial modeling of haplotype associations. Hum Hered. 2003;56 (1-3):32-40. doi: 10.1159/000073730. PubMed PMID:14614236 .
  417. Loukola, A, Chadha, M, Penn, SG, Rank, D, Conti, DV, Thompson, D et al.. Comprehensive evaluation of the association between prostate cancer and genotypes/haplotypes in CYP17A1, CYP3A4, and SRD5A2. Eur J Hum Genet. 2004;12 (4):321-32. doi: 10.1038/sj.ejhg.5201101. PubMed PMID:14560315 .
  418. Plummer, SJ, Conti, DV, Paris, PL, Curran, AP, Casey, G, Witte, JS et al.. CYP3A4 and CYP3A5 genotypes, haplotypes, and risk of prostate cancer. Cancer Epidemiol Biomarkers Prev. 2003;12 (9):928-32. . PubMed PMID:14504207 .
  419. Neville, PJ, Conti, DV, Krumroy, LM, Catalona, WJ, Suarez, BK, Witte, JS et al.. Prostate cancer aggressiveness locus on chromosome segment 19q12-q13.1 identified by linkage and allelic imbalance studies. Genes Chromosomes Cancer. 2003;36 (4):332-9. doi: 10.1002/gcc.10165. PubMed PMID:12619157 .
  420. Conti, DV, Witte, JS. Hierarchical modeling of linkage disequilibrium: genetic structure and spatial relations. Am J Hum Genet. 2003;72 (2):351-63. doi: 10.1086/346117. PubMed PMID:12525994 PubMed Central PMC379228.
  421. Neville, PJ, Conti, DV, Paris, PL, Levin, H, Catalona, WJ, Suarez, BK et al.. Prostate cancer aggressiveness locus on chromosome 7q32-q33 identified by linkage and allelic imbalance studies. Neoplasia. 2002;4 (5):424-31. doi: 10.1038/sj.neo.7900254. PubMed PMID:12192601 PubMed Central PMC1564121.
  422. Yamamoto, S, Hanley, E, Hahn, AB, Isenberg, A, Singh, TP, Cohen, D et al.. The impact of obesity in renal transplantation: an analysis of paired cadaver kidneys. Clin Transplant. 2002;16 (4):252-6. doi: 10.1034/j.1399-0012.2002.01080.x. PubMed PMID:12099980 .
  423. Vargas, H, Nazeer, T, Conti, D, Parnes, SM. Posttransplant lymphoproliferative disorder of the nasopharynx. Am J Rhinol. 2002;16 (1):37-42. . PubMed PMID:11895192 .
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