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Proteomic and Metabolomic Signatures of Diet Quality in Young Adults.
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Associations of dietary intake and longitudinal measures of per- and polyfluoroalkyl substances (PFAS) in predominantly Hispanic young Adults: A multicohort study.
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Combining magnetic resonance imaging with a multi-ancestry polygenic risk score to improve identification of clinically-significant prostate cancer.
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Identification of Genes with Rare Loss of Function Variants Associated with Aggressive Prostate Cancer and Survival.
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Exposure to 4,4'-DDE in visceral adipose tissue and weight loss in adolescents from the Teen-LABS cohort.
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Exposure to per- and polyfluoroalkyl substances and high-throughput proteomics in Hispanic youth.
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Metabolic Signatures of Youth Exposure to Mixtures of Per- and Polyfluoroalkyl Substances: A Multi-Cohort Study.
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Combining Asian-European Genome-Wide Association Studies of Colorectal Cancer Improves Risk Prediction Across Race and Ethnicity.
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RE: Polygenic risk of any, metastatic, and fatal prostate cancer in the Million Veteran Program.
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The Contribution of Germline Pathogenic Variants in Breast Cancer Genes to Contralateral Breast Cancer Risk in BRCA1/BRCA2/PALB2-Negative Women.
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Evidence of Novel Susceptibility Variants for Prostate Cancer and a Multiancestry Polygenic Risk Score Associated with Aggressive Disease in Men of African Ancestry.
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Transcriptome-Wide Association Analysis Identifies Novel Candidate Susceptibility Genes for Prostate-Specific Antigen Levels in Men Without Prostate Cancer.
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Evaluating approaches for constructing polygenic risk scores for prostate cancer in men of African and European ancestry.
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Evaluating Approaches for Constructing Polygenic Risk Scores for Prostate Cancer in Men of African and European Ancestry.
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Germline Sequencing Analysis to Inform Clinical Gene Panel Testing for Aggressive Prostate Cancer.
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Correction: Distinct germline genetic susceptibility profiles identified for common non-Hodgkin lymphoma subtypes.
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Paired Liver:Plasma PFAS Concentration Ratios from Adolescents in the Teen-LABS Study and Derivation of Empirical and Mass Balance Models to Predict and Explain Liver PFAS Accumulation.
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Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations.
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Estimating heritability explained by local ancestry and evaluating stratification bias in admixture mapping from summary statistics.
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Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants.
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Excess pancreatic cancer risk due to smoking and modifying effect of quitting smoking: The Multiethnic Cohort Study.
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Polygenic Risk Score Modifies Prostate Cancer Risk of Pathogenic Variants in Men of African Ancestry.
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Postprandial Metabolite Profiles and Risk of Prediabetes in Young People: A Longitudinal Multicohort Study.
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Genome-wide gene-environment interaction analyses to understand the relationship between red meat and processed meat intake and colorectal cancer risk.
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A Rare Germline HOXB13 Variant Contributes to Risk of Prostate Cancer in Men of African Ancestry.
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Genetic Risk of Second Primary Cancer in Breast Cancer Survivors: The Multiethnic Cohort Study.
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Validation of a multi-ancestry polygenic risk score and age-specific risks of prostate cancer: A meta-analysis within diverse populations.
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Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits-The Hispanic/Latino Anthropometry Consortium.
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Exposure to per- and Polyfluoroalkyl Substances and Markers of Liver Injury: A Systematic Review and Meta-Analysis.
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Plasma concentrations of lipophilic persistent organic pollutants and glucose homeostasis in youth populations.
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Genome-Wide Interaction Analysis of Genetic Variants with Menopausal Hormone Therapy for Colorectal Cancer Risk.
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Urinary metabolic biomarkers of diet quality in European children are associated with metabolic health.
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Prenatal exposure to multiple organochlorine compounds and childhood body mass index.
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Characteristics associated with COVID-19 vaccination status among staff and faculty of a large, diverse University in Los Angeles: The Trojan Pandemic Response Initiative.
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Polygenic Risk Scores for Prediction of Breast Cancer Risk in Women of African Ancestry: a Cross-Ancestry Approach.
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Beyond GWAS of Colorectal Cancer: Evidence of Interaction with Alcohol Consumption and Putative Causal Variant for the 10q24.2 Region.
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Circulating free testosterone and risk of aggressive prostate cancer: Prospective and Mendelian randomisation analyses in international consortia.
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Circulating insulin-like growth factors and risks of overall, aggressive and early-onset prostate cancer: a collaborative analysis of 20 prospective studies and Mendelian randomization analysis.
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Clonal hematopoiesis and risk of prostate cancer in large samples of European ancestry men.
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Diet Quality Is Associated with Glucose Regulation in a Cohort of Young Adults.
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Genome-wide interaction study with smoking for colorectal cancer risk identifies novel genetic loci related to tumor suppression, inflammation and immune response.
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Distinct germline genetic susceptibility profiles identified for common non-Hodgkin lymphoma subtypes.
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Association of Prostate-Specific Antigen Levels with Prostate Cancer Risk in a Multiethnic Population: Stability Over Time and Comparison with Polygenic Risk Score.
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Testing the generalizability of ancestry-specific polygenic risk scores to predict prostate cancer in sub-Saharan Africa.
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Genetic architectures of proximal and distal colorectal cancer are partly distinct.
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A Hierarchical Approach Using Marginal Summary Statistics for Multiple Intermediates in a Mendelian Randomization or Transcriptome Analysis.
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Prenatal metal mixtures and child blood pressure in the Rhea mother-child cohort in Greece.
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In Utero Exposure to Mercury Is Associated With Increased Susceptibility to Liver Injury and Inflammation in Childhood.
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Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry.
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Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction.
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Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction.
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Evaluation of a Multiethnic Polygenic Risk Score Model for Prostate Cancer.
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Evaluating Polygenic Risk Scores for Breast Cancer in Women of African Ancestry.
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Rare Variants in the DNA Repair Pathway and the Risk of Colorectal Cancer.
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The International Family Study of Nonsyndromic Orofacial Clefts: Design and Methods.
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Identifying Novel Susceptibility Genes for Colorectal Cancer Risk From a Transcriptome-Wide Association Study of 125,478 Subjects.
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Bayesian variable selection with a pleiotropic loss function in Mendelian randomization.
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Novel strategy for disease risk prediction incorporating predicted gene expression and DNA methylation data: a multi-phased study of prostate cancer.
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Combined Effect of a Polygenic Risk Score and Rare Genetic Variants on Prostate Cancer Risk.
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A genetic association study of tobacco withdrawal endophenotypes in African Americans.
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Cross-ancestry GWAS meta-analysis identifies six breast cancer loci in African and European ancestry women.
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An integrated risk and epidemiological model to estimate risk-stratified COVID-19 outcomes for Los Angeles County: March 1, 2020-March 1, 2021.
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Lymphoma-Associated Biomarkers Are Increased in Current Smokers in Twin Pairs Discordant for Smoking.
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Exposure to Perfluoroalkyl Substances and Glucose Homeostasis in Youth.
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Association of Genetic Risk Score With NAFLD in An Ethnically Diverse Cohort.
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A Cross-Sectional Study Examining the Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus 2 Antibodies in a University Student Population.
J Adolesc Health. 2020 Dec;67(6):763-768. doi: 10.1016/j.jadohealth.2020.09.001. Epub 2020 Oct 15. PubMed PMID: 33071164; PubMed Central PMCID: PMC7557277.
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Functional informed genome-wide interaction analysis of body mass index, diabetes and colorectal cancer risk.
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A latent unknown clustering integrating multi-omics data (LUCID) with phenotypic traits.
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Author Correction: Elevated numbers of PD-L1 expressing B cells are associated with the development of AIDS-NHL.
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A Germline Variant at 8q24 Contributes to Familial Clustering of Prostate Cancer in Men of African Ancestry.
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Dysregulated lipid and fatty acid metabolism link perfluoroalkyl substances exposure and impaired glucose metabolism in young adults.
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A meta-analysis of genome-wide association studies of multiple myeloma among men and women of African ancestry.
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A genome-wide association study of prostate cancer in Latinos.
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Prenatal Exposure to Perfluoroalkyl Substances Associated With Increased Susceptibility to Liver Injury in Children.
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Association of Fish Consumption and Mercury Exposure During Pregnancy With Metabolic Health and Inflammatory Biomarkers in Children.
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Perfluoroalkyl substances and severity of nonalcoholic fatty liver in Children: An untargeted metabolomics approach.
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Replication and Genetic Risk Score Analysis for Pancreatic Cancer in a Diverse Multiethnic Population.
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Pathogenic Variants in Cancer Predisposition Genes and Prostate Cancer Risk in Men of African Ancestry.
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Variability in Cytogenetic Testing for Multiple Myeloma: A Comprehensive Analysis From Across the United States.
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Estimation of COVID-19 risk-stratified epidemiological parameters and policy implications for Los Angeles County through an integrated risk and stochastic epidemiological model.
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The role of smoke from cooking indoors over an open flame and parental smoking on the risk of cleft lip and palate: A case- control study in 7 low-resource countries.
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Interaction effect of alcohol consumption and Alzheimer disease polygenic risk score on the brain cortical thickness of cognitively normal subjects.
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Infectious mononucleosis, immune genotypes, and non-Hodgkin lymphoma (NHL): an InterLymph Consortium study.
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Mendelian Randomization of Circulating Polyunsaturated Fatty Acids and Colorectal Cancer Risk.
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The genetic diversity of multiple sclerosis risk among Hispanic and African American populations living in the United States.
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The Four-Kallikrein Panel Is Effective in Identifying Aggressive Prostate Cancer in a Multiethnic Population.
Cancer Epidemiol Biomarkers Prev. 2020 Jul;29(7):1381-1388. doi: 10.1158/1055-9965.EPI-19-1560. Epub 2020 May 8. PubMed PMID: 32385116; PubMed Central PMCID: PMC7334056.
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An integrative multi-omics analysis to identify candidate DNA methylation biomarkers related to prostate cancer risk.
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Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan.
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Correction to: Infectious mononucleosis, immune genotypes, and non-Hodgkin lymphoma (NHL): an InterLymph Consortium study.
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Alterations in folate-dependent one-carbon metabolism as colon cell transition from normal to cancerous.
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Exploratory metabolomic study to identify blood-based biomarkers as a potential screen for colorectal cancer.
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Elucidation of causal direction between asthma and obesity: a bi-directional Mendelian randomization study.
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Using Bayes model averaging to leverage both gene main effects and G ×  E interactions to identify genomic regions in genome-wide association studies.
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HiLDA: a statistical approach to investigate differences in mutational signatures.
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A Unified Model for the Analysis of Gene-Environment Interaction.
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Association of a Pathway-Specific Genetic Risk Score With Risk of Radiation-Associated Contralateral Breast Cancer.
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Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes.
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Correction to: Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer.
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Discovery of common and rare genetic risk variants for colorectal cancer.
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Perfluoroalkyl substances, metabolomic profiling, and alterations in glucose homeostasis among overweight and obese Hispanic children: A proof-of-concept analysis.
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Epstein-Barr virus load is higher in long-term Hodgkin lymphoma survivors compared to their unaffected twins and unrelated controls.
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Elevated numbers of PD-L1 expressing B cells are associated with the development of AIDS-NHL.
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An admixture mapping meta-analysis implicates genetic variation at 18q21 with asthma susceptibility in Latinos.
J Allergy Clin Immunol. 2019 Mar;143(3):957-969. doi: 10.1016/j.jaci.2016.08.057. Epub 2018 Sep 7. PubMed PMID: 30201514; PubMed Central PMCID: PMC6927816.
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DNA methylation patterns of adult survivors of adolescent/young adult Hodgkin lymphoma compared to their unaffected monozygotic twin.
Leuk Lymphoma. 2019 Jun;60(6):1429-1437. doi: 10.1080/10428194.2018.1533128. Epub 2019 Jan 22. PubMed PMID: 30668190; PubMed Central PMCID: PMC7781082.
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Improvements to the Escalation with Overdose Control design and a comparison with the restricted Continual Reassessment Method.
Pharm Stat. 2019 Nov;18(6):659-670. doi: 10.1002/pst.1955. Epub 2019 Jun 25. PubMed PMID: 31237419;
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Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer.
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Publisher Correction: Shared heritability and functional enrichment across six solid cancers.
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Shared heritability and functional enrichment across six solid cancers.
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Correction: Rare germline variants in DNA repair genes and the angiogenesis pathway predispose prostate cancer patients to develop metastatic disease.
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Novel Common Genetic Susceptibility Loci for Colorectal Cancer.
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Large-Scale Genome-Wide Association Study of East Asians Identifies Loci Associated With Risk for Colorectal Cancer.
Gastroenterology. 2019 Apr;156(5):1455-1466. doi: 10.1053/j.gastro.2018.11.066. Epub 2018 Dec 6. PubMed PMID: 30529582; PubMed Central PMCID: PMC6441622.
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Genome-wide association study of circulating folate one-carbon metabolites.
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Telomerase Variants in Patients with Cirrhosis Awaiting Liver Transplantation.
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Germline DNA Repair Gene Mutations in Young-onset Prostate Cancer Cases in the UK: Evidence for a More Extensive Genetic Panel.
Eur Urol. 2019 Sep;76(3):329-337. doi: 10.1016/j.eururo.2019.01.050. Epub 2019 Feb 15. PubMed PMID: 30777372; PubMed Central PMCID: PMC6695475.
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Reply to Xiaoling Lin, Brian T. Helfand, and Jianfeng Xu's Letter to the Editor re: Daniel A. Leongamornlert, Edward J. Saunders, Sarah Wakerell, et al. Germline DNA Repair Gene Mutations in Young-onset Prostate Cancer Cases in the UK: Evidence for a More Extensive Genetic Panel. Eur Urol 2019;76:329-37.
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Author Correction: Germline variation at 8q24 and prostate cancer risk in men of European ancestry.
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Author Correction: Large-scale transcriptome-wide association study identifies new prostate cancer risk regions.
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Association analyses identify 31 new risk loci for colorectal cancer susceptibility.
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Author Correction: Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia.
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Author Correction: Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma.
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Author Correction: Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility.
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Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.
Nat Genet. 2019 Feb;51(2):363. doi: 10.1038/s41588-018-0330-6. PubMed PMID: 30622367;
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Circulating Metabolic Biomarkers of Screen-Detected Prostate Cancer in the ProtecT Study.
Cancer Epidemiol Biomarkers Prev. 2019 Jan;28(1):208-216. doi: 10.1158/1055-9965.EPI-18-0079. Epub 2018 Oct 23. PubMed PMID: 30352818; PubMed Central PMCID: PMC6746173.
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Evaluation of 71 Coronary Artery Disease Risk Variants in a Multiethnic Cohort.
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Native ancestry is associated with optic neuritis and age of onset in hispanics with multiple sclerosis.
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Rare germline variants in DNA repair genes and the angiogenesis pathway predispose prostate cancer patients to develop metastatic disease.
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Germline variation at 8q24 and prostate cancer risk in men of European ancestry.
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Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.
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Genetic risk of prostate cancer in Ugandan men.
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Breast Cancer Family History and Contralateral Breast Cancer Risk in Young Women: An Update From the Women's Environmental Cancer and Radiation Epidemiology Study.
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Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants.
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CYP2D6 phenotype, tamoxifen, and risk of contralateral breast cancer in the WECARE Study.
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Large-scale transcriptome-wide association study identifies new prostate cancer risk regions.
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Simultaneous quantitation of folates, flavins and B<sub>6</sub> metabolites in human plasma by LC-MS/MS assay: Applications in colorectal cancer.
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Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma.
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Revealing the complex genetic architecture of obsessive-compulsive disorder using meta-analysis.
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Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia.
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The association of mammographic density with risk of contralateral breast cancer and change in density with treatment in the WECARE study.
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Update on the State of the Science for Analytical Methods for Gene-Environment Interactions.
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Incorporation of Biological Knowledge Into the Study of Gene-Environment Interactions.
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Characterizing Genetic Susceptibility to Breast Cancer in Women of African Ancestry.
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Novel colon cancer susceptibility variants identified from a genome-wide association study in African Americans.
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Inherited variation in circadian rhythm genes and risks of prostate cancer and three other cancer sites in combined cancer consortia.
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Two Novel Susceptibility Loci for Prostate Cancer in Men of African Ancestry.
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The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers.
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Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility.
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Pro-inflammatory fatty acid profile and colorectal cancer risk: A Mendelian randomisation analysis.
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Investigating the genetic relationship between Alzheimer's disease and cancer using GWAS summary statistics.
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Quantifying the Genetic Correlation between Multiple Cancer Types.
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Mendelian randomisation implicates hyperlipidaemia as a risk factor for colorectal cancer.
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Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium.
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Common variants in the obesity-associated genes FTO and MC4R are not associated with risk of colorectal cancer.
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Fine-Mapping of Common Genetic Variants Associated with Colorectal Tumor Risk Identified Potential Functional Variants.
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Detecting Gene-Environment Interactions for a Quantitative Trait in a Genome-Wide Association Study.
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GWASeq: targeted re-sequencing follow up to GWAS.
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Identification of a novel susceptibility locus at 13q34 and refinement of the 20p12.2 region as a multi-signal locus associated with bladder cancer risk in individuals of European ancestry.
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A Meta-analysis of Multiple Myeloma Risk Regions in African and European Ancestry Populations Identifies Putatively Functional Loci.
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Developmental changes in genetic and environmental influences on Chinese child and adolescent anxiety and depression.
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Genome-Wide Association of the Laboratory-Based Nicotine Metabolite Ratio in Three Ancestries.
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Genome-wide association study of colorectal cancer in Hispanics.
Carcinogenesis. 2016 Jun;37(6):547-556. doi: 10.1093/carcin/bgw046. Epub 2016 Apr 18. PubMed PMID: 27207650; PubMed Central PMCID: PMC4876992.
PubMed

Reducing GWAS Complexity.
Cell Cycle. 2016;15(1):22-4. doi: 10.1080/15384101.2015.1120928. PubMed PMID: 26771711; PubMed Central PMCID: PMC4825730.
PubMed

Prostate Cancer Susceptibility in Men of African Ancestry at 8q24.
J Natl Cancer Inst. 2016 Jul;108(7). doi: 10.1093/jnci/djv431. Epub 2016 Jan 27. PubMed PMID: 26823525; PubMed Central PMCID: PMC4948565.
PubMed

JAM: A Scalable Bayesian Framework for Joint Analysis of Marginal SNP Effects.
Genet Epidemiol. 2016 Apr;40(3):188-201. doi: 10.1002/gepi.21953. PubMed PMID: 27027514; PubMed Central PMCID: PMC4817278.
PubMed

Smokescreen: a targeted genotyping array for addiction research.
BMC Genomics. 2016 Feb 27;17:145. doi: 10.1186/s12864-016-2495-7. Epub 2016 Feb 27. PubMed PMID: 26921259; PubMed Central PMCID: PMC4769529.
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Whole-exome sequencing of over 4100 men of African ancestry and prostate cancer risk.
Hum Mol Genet. 2016 Jan 15;25(2):371-81. doi: 10.1093/hmg/ddv462. Epub 2015 Nov 24. PubMed PMID: 26604137; PubMed Central PMCID: PMC4865031.
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The contribution of rare variation to prostate cancer heritability.
Nat Genet. 2016 Jan;48(1):30-5. doi: 10.1038/ng.3446. Epub 2015 Nov 16. PubMed PMID: 26569126; PubMed Central PMCID: PMC7534691.
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Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation.
Nat Commun. 2016 Apr 7;7:10979. doi: 10.1038/ncomms10979. Epub 2016 Apr 7. PubMed PMID: 27052111; PubMed Central PMCID: PMC4829663.
PubMed

Body mass index, weight change, and risk of second primary breast cancer in the WECARE study: influence of estrogen receptor status of the first breast cancer.
Cancer Med. 2016 Nov;5(11):3282-3291. doi: 10.1002/cam4.890. Epub 2016 Oct 3. PubMed PMID: 27700016; PubMed Central PMCID: PMC5119984.
PubMed

Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer.
Br J Cancer. 2016 Jul 12;115(2):266-72. doi: 10.1038/bjc.2016.188. Epub 2016 Jun 23. PubMed PMID: 27336604; PubMed Central PMCID: PMC4947703.
PubMed

Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease.
Hum Mol Genet. 2016 Jun 1;25(11):2349-2359. doi: 10.1093/hmg/ddw087. Epub 2016 Mar 22. PubMed PMID: 27005424; PubMed Central PMCID: PMC5081051.
PubMed

Identification of Susceptibility Loci and Genes for Colorectal Cancer Risk.
Gastroenterology. 2016 Jun;150(7):1633-1645. doi: 10.1053/j.gastro.2016.02.076. Epub 2016 Mar 8. PubMed PMID: 26965516; PubMed Central PMCID: PMC4909543.
PubMed

Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
Cancer Res. 2016 Sep 1;76(17):5103-14. doi: 10.1158/0008-5472.CAN-15-2980. Epub 2016 Apr 20. PubMed PMID: 27197191; PubMed Central PMCID: PMC5010493.
PubMed

Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population.
J Clin Oncol. 2015 Sep 10;33(26):2901-7. doi: 10.1200/JCO.2015.61.2408. Epub 2015 Aug 10. PubMed PMID: 26261251; PubMed Central PMCID: PMC4554751.
PubMed

Enlight: web-based integration of GWAS results with biological annotations.
Bioinformatics. 2015 Jan 15;31(2):275-6. doi: 10.1093/bioinformatics/btu639. Epub 2014 Sep 26. PubMed PMID: 25262152; PubMed Central PMCID: PMC4287951.
PubMed

Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD.
Am J Psychiatry. 2015 Jan;172(1):82-93. doi: 10.1176/appi.ajp.2014.13101306. Epub 2014 Oct 31. PubMed PMID: 25158072; PubMed Central PMCID: PMC4282594.
PubMed

Corrigendum: genome-wide association study of colorectal cancer identifies six new susceptibility loci.
Nat Commun. 2015 Oct 26;6:8739. doi: 10.1038/ncomms9739. Epub 2015 Oct 26. PubMed PMID: 26498495;
PubMed

Genome-wide association study of colorectal cancer identifies six new susceptibility loci.
Nat Commun. 2015 Jul 7;6:7138. doi: 10.1038/ncomms8138. Epub 2015 Jul 7. PubMed PMID: 26151821; PubMed Central PMCID: PMC4967357.
PubMed

Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions.
Hum Mol Genet. 2015 Oct 1;24(19):5603-18. doi: 10.1093/hmg/ddv269. Epub 2015 Jul 10. PubMed PMID: 26162851; PubMed Central PMCID: PMC4572069.
PubMed

Identification of a Novel Mucin Gene HCG22 Associated With Steroid-Induced Ocular Hypertension.
Invest Ophthalmol Vis Sci. 2015 Apr;56(4):2737-48. doi: 10.1167/iovs.14-14803. PubMed PMID: 25813999; PubMed Central PMCID: PMC4416661.
PubMed

Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for Thirteen Cancer Types.
J Natl Cancer Inst. 2015 Dec;107(12):djv279. doi: 10.1093/jnci/djv279. Epub 2015 Oct 12. PubMed PMID: 26464424; PubMed Central PMCID: PMC4806328.
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Genetic ancestry influences asthma susceptibility and lung function among Latinos.
J Allergy Clin Immunol. 2015 Jan;135(1):228-35. doi: 10.1016/j.jaci.2014.07.053. Epub 2014 Oct 6. PubMed PMID: 25301036; PubMed Central PMCID: PMC4289103.
PubMed

Germline Mutations in the BRIP1, BARD1, PALB2, and NBN Genes in Women With Ovarian Cancer.
J Natl Cancer Inst. 2015 Nov;107(11). doi: 10.1093/jnci/djv214. Epub 2015 Aug 27. PubMed PMID: 26315354; PubMed Central PMCID: PMC4643629.
PubMed

Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans.
Hum Mol Genet. 2015 Oct 1;24(19):5589-602. doi: 10.1093/hmg/ddv203. Epub 2015 May 29. PubMed PMID: 26025378; PubMed Central PMCID: PMC4572072.
PubMed

Identification of a common variant with potential pleiotropic effect on risk of inflammatory bowel disease and colorectal cancer.
Carcinogenesis. 2015 Sep;36(9):999-1007. doi: 10.1093/carcin/bgv086. Epub 2015 Jun 12. PubMed PMID: 26071399; PubMed Central PMCID: PMC4573660.
PubMed

UGT1A and UGT2B genetic variation alters nicotine and nitrosamine glucuronidation in european and african american smokers.
Cancer Epidemiol Biomarkers Prev. 2015 Jan;24(1):94-104. doi: 10.1158/1055-9965.EPI-14-0804. Epub 2014 Oct 2. PubMed PMID: 25277794; PubMed Central PMCID: PMC4294984.
PubMed

Place of birth,age of immigration,and disability in Hispanics with multiple sclerosis.
Mult Scler Relat Disord. 2015 Jan;4(1):25-30. doi: 10.1016/j.msard.2014.11.008. PubMed PMID: 25729639; PubMed Central PMCID: PMC4341972.
PubMed

Generalizability of established prostate cancer risk variants in men of African ancestry.
Int J Cancer. 2015 Mar 1;136(5):1210-7. doi: 10.1002/ijc.29066. Epub 2014 Jul 15. PubMed PMID: 25044450; PubMed Central PMCID: PMC4268262.
PubMed

Drug Metabolizing Enzyme and Transporter Gene Variation, Nicotine Metabolism, Prospective Abstinence, and Cigarette Consumption.
PLoS One. 2015;10(7):e0126113. doi: 10.1371/journal.pone.0126113. Epub 2015 Jul 1. PubMed PMID: 26132489; PubMed Central PMCID: PMC4488893.
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Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.
Sci Rep. 2015 Dec 1;5:17369. doi: 10.1038/srep17369. Epub 2015 Dec 1. PubMed PMID: 26621817; PubMed Central PMCID: PMC4664893.
PubMed

Erratum: A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer.
Sci Rep. 2015 Aug 3;5:12372. doi: 10.1038/srep12372. Epub 2015 Aug 3. PubMed PMID: 26237130; PubMed Central PMCID: PMC4523102.
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A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer.
Sci Rep. 2015 May 20;5:10442. doi: 10.1038/srep10442. Epub 2015 May 20. PubMed PMID: 25990418; PubMed Central PMCID: PMC4438486.
PubMed

Common colorectal cancer risk alleles contribute to the multiple colorectal adenoma phenotype, but do not influence colonic polyposis in FAP.
Eur J Hum Genet. 2015 Feb;23(2):260-3. doi: 10.1038/ejhg.2014.74. Epub 2014 May 7. PubMed PMID: 24801760; PubMed Central PMCID: PMC4140766.
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A novel colorectal cancer risk locus at 4q32.2 identified from an international genome-wide association study.
Carcinogenesis. 2014 Nov;35(11):2512-9. doi: 10.1093/carcin/bgu148. Epub 2014 Jul 14. PubMed PMID: 25023989; PubMed Central PMCID: PMC4271131.
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Gender difference in interactions between MAOA promoter uVNTR polymorphism and negative familial stressors on body mass index among Chinese adolescents.
Pediatr Obes. 2014 Oct;9(5):e80-90. doi: 10.1111/j.2047-6310.2013.00181.x. Epub 2013 Jun 13. PubMed PMID: 23761378; PubMed Central PMCID: PMC4159439.
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A meta-analysis of Hodgkin lymphoma reveals 19p13.3 TCF3 as a novel susceptibility locus.
Nat Commun. 2014 Jun 12;5:3856. doi: 10.1038/ncomms4856. Epub 2014 Jun 12. PubMed PMID: 24920014; PubMed Central PMCID: PMC4055950.
PubMed

Identification and characterization of functional risk variants for colorectal cancer mapping to chromosome 11q23.1.
Hum Mol Genet. 2014 Apr 15;23(8):2198-209. doi: 10.1093/hmg/ddt584. Epub 2013 Nov 20. PubMed PMID: 24256810; PubMed Central PMCID: PMC3959808.
PubMed

Genome-wide interaction study of smoking and bladder cancer risk.
Carcinogenesis. 2014 Aug;35(8):1737-44. doi: 10.1093/carcin/bgu064. Epub 2014 Mar 24. PubMed PMID: 24662972; PubMed Central PMCID: PMC4123644.
PubMed

Comprehensive analyses of DNA repair pathways, smoking and bladder cancer risk in Los Angeles and Shanghai.
Int J Cancer. 2014 Jul 15;135(2):335-47. doi: 10.1002/ijc.28693. Epub 2014 Jan 13. PubMed PMID: 24382701; PubMed Central PMCID: PMC4016180.
PubMed

Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33.
Hum Mol Genet. 2014 Dec 15;23(24):6616-33. doi: 10.1093/hmg/ddu363. Epub 2014 Jul 15. PubMed PMID: 25027329; PubMed Central PMCID: PMC4240198.
PubMed

A comprehensive examination of breast cancer risk loci in African American women.
Hum Mol Genet. 2014 Oct 15;23(20):5518-26. doi: 10.1093/hmg/ddu252. Epub 2014 May 22. PubMed PMID: 24852375; PubMed Central PMCID: PMC4168823.
PubMed

The 19q12 bladder cancer GWAS signal: association with cyclin E function and aggressive disease.
Cancer Res. 2014 Oct 15;74(20):5808-18. doi: 10.1158/0008-5472.CAN-14-1531. PubMed PMID: 25320178; PubMed Central PMCID: PMC4203382.
PubMed

Genome-wide association study identifies multiple loci associated with bladder cancer risk.
Hum Mol Genet. 2014 Mar 1;23(5):1387-98. doi: 10.1093/hmg/ddt519. Epub 2013 Oct 24. PubMed PMID: 24163127; PubMed Central PMCID: PMC3919005.
PubMed

Pleiotropic effects of genetic risk variants for other cancers on colorectal cancer risk: PAGE, GECCO and CCFR consortia.
Gut. 2014 May;63(5):800-7. doi: 10.1136/gutjnl-2013-305189. Epub 2013 Aug 9. PubMed PMID: 23935004; PubMed Central PMCID: PMC3918490.
PubMed

Nicotine dependence as a moderator of genetic influences on smoking cessation treatment outcome.
Drug Alcohol Depend. 2014 May 1;138:109-17. doi: 10.1016/j.drugalcdep.2014.02.016. Epub 2014 Mar 5. PubMed PMID: 24667010; PubMed Central PMCID: PMC4095777.
PubMed

Organic cation transporter variation and response to smoking cessation therapies.
Nicotine Tob Res. 2014 Dec;16(12):1638-46. doi: 10.1093/ntr/ntu161. Epub 2014 Aug 20. PubMed PMID: 25143296; PubMed Central PMCID: PMC4296186.
PubMed

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer.
Nat Genet. 2014 Oct;46(10):1103-9. doi: 10.1038/ng.3094. Epub 2014 Sep 14. PubMed PMID: 25217961; PubMed Central PMCID: PMC4383163.
PubMed

Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A.
Nat Commun. 2014 Aug 8;5:4613. doi: 10.1038/ncomms5613. Epub 2014 Aug 8. PubMed PMID: 25105248; PubMed Central PMCID: PMC4180879.
PubMed

Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis.
Hum Mol Genet. 2014 Sep 1;23(17):4729-37. doi: 10.1093/hmg/ddu177. Epub 2014 Apr 15. PubMed PMID: 24737748; PubMed Central PMCID: PMC4133584.
PubMed

Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk.
Nat Genet. 2014 Jun;46(6):533-42. doi: 10.1038/ng.2985. Epub 2014 May 18. PubMed PMID: 24836286; PubMed Central PMCID: PMC4068797.
PubMed

A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age.
Cancer Epidemiol Biomarkers Prev. 2014 Apr;23(4):658-69. doi: 10.1158/1055-9965.EPI-13-0340. Epub 2014 Feb 3. PubMed PMID: 24493630; PubMed Central PMCID: PMC3990360.
PubMed

Deciphering the genetic architecture of low-penetrance susceptibility to colorectal cancer.
Hum Mol Genet. 2013 Dec 15;22(24):5075-82. doi: 10.1093/hmg/ddt357. Epub 2013 Jul 30. PubMed PMID: 23904454; PubMed Central PMCID: PMC3836483.
PubMed

Genetic predictors of circulating 25-hydroxyvitamin d and risk of colorectal cancer.
Cancer Epidemiol Biomarkers Prev. 2013 Nov;22(11):2037-46. doi: 10.1158/1055-9965.EPI-13-0209. Epub 2013 Aug 27. PubMed PMID: 23983240; PubMed Central PMCID: PMC3818310.
PubMed

A scalable, knowledge-based analysis framework for genetic association studies.
BMC Bioinformatics. 2013 Oct 23;14:312. doi: 10.1186/1471-2105-14-312. Epub 2013 Oct 23. PubMed PMID: 24152222; PubMed Central PMCID: PMC4015032.
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Biomarkers for smoking cessation.
Clin Pharmacol Ther. 2013 Jun;93(6):526-38. doi: 10.1038/clpt.2013.57. Epub 2013 Mar 18. PubMed PMID: 23588313; PubMed Central PMCID: PMC3772534.
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Efficient two-step testing of gene-gene interactions in genome-wide association studies.
Genet Epidemiol. 2013 Jul;37(5):440-51. doi: 10.1002/gepi.21720. Epub 2013 Apr 30. PubMed PMID: 23633124;
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A Bayesian Hierarchical Model for Relating Multiple SNPs within Multiple Genes to Disease Risk.
Int J Genomics. 2013;2013:406217. doi: 10.1155/2013/406217. Epub 2013 Dec 31. PubMed PMID: 24490143; PubMed Central PMCID: PMC3892936.
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Elevated 4-aminobiphenyl and 2,6-dimethylaniline hemoglobin adducts and increased risk of bladder cancer among lifelong nonsmokers--The Shanghai Bladder Cancer Study.
Cancer Epidemiol Biomarkers Prev. 2013 May;22(5):937-45. doi: 10.1158/1055-9965.EPI-12-1447. Epub 2013 Mar 28. PubMed PMID: 23539508; PubMed Central PMCID: PMC4065796.
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Genetic variations in SMAD7 are associated with colorectal cancer risk in the colon cancer family registry.
PLoS One. 2013;8(4):e60464. doi: 10.1371/journal.pone.0060464. Epub 2013 Apr 3. PubMed PMID: 23560096; PubMed Central PMCID: PMC3616155.
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Confounding and heterogeneity in genetic association studies with admixed populations.
Am J Epidemiol. 2013 Feb 15;177(4):351-60. doi: 10.1093/aje/kws234. Epub 2013 Jan 18. PubMed PMID: 23334005; PubMed Central PMCID: PMC3626055.
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Influence of a dopamine pathway additive genetic efficacy score on smoking cessation: results from two randomized clinical trials of bupropion.
Addiction. 2013 Dec;108(12):2202-11. doi: 10.1111/add.12325. Epub 2013 Sep 18. PubMed PMID: 23941313; PubMed Central PMCID: PMC3834197.
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Genome-wide association study of Tourette's syndrome.
Mol Psychiatry. 2013 Jun;18(6):721-8. doi: 10.1038/mp.2012.69. Epub 2012 Aug 14. PubMed PMID: 22889924; PubMed Central PMCID: PMC3605224.
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Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.
Gastroenterology. 2013 Apr;144(4):799-807.e24. doi: 10.1053/j.gastro.2012.12.020. Epub 2012 Dec 22. PubMed PMID: 23266556; PubMed Central PMCID: PMC3636812.
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Integrative variable selection via Bayesian model uncertainty.
Stat Med. 2013 Dec 10;32(28):4938-53. doi: 10.1002/sim.5888. Epub 2013 Jul 3. PubMed PMID: 23824835; PubMed Central PMCID: PMC4085544.
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Sneaker "jack" males outcompete dominant "hooknose" males under sperm competition in Chinook salmon (Oncorhynchus tshawytscha).
Ecol Evol. 2013 Dec;3(15):4987-97. doi: 10.1002/ece3.869. Epub 2013 Nov 11. PubMed PMID: 24455130; PubMed Central PMCID: PMC3892362.
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Spinal cord lesions and disability in Hispanics with multiple sclerosis.
J Neurol. 2013 Nov;260(11):2770-6. doi: 10.1007/s00415-013-7054-4. Epub 2013 Aug 3. PubMed PMID: 23912723; PubMed Central PMCID: PMC3816004.
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Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture.
PLoS Genet. 2013 Oct;9(10):e1003864. doi: 10.1371/journal.pgen.1003864. Epub 2013 Oct 24. PubMed PMID: 24204291; PubMed Central PMCID: PMC3812053.
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Genome-wide association study of obsessive-compulsive disorder.
Mol Psychiatry. 2013 Jul;18(7):788-98. doi: 10.1038/mp.2012.85. Epub 2012 Aug 14. PubMed PMID: 22889921; PubMed Central PMCID: PMC4218751.
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The DRD4 exon III VNTR, bupropion, and associations with prospective abstinence.
Nicotine Tob Res. 2013 Jul;15(7):1190-200. doi: 10.1093/ntr/nts245. Epub 2012 Dec 3. PubMed PMID: 23212438; PubMed Central PMCID: PMC3682839.
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Nicotinic acetylcholine receptor variation and response to smoking cessation therapies.
Pharmacogenet Genomics. 2013 Feb;23(2):94-103. doi: 10.1097/FPC.0b013e32835cdabd. PubMed PMID: 23249876; PubMed Central PMCID: PMC3563676.
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Next generation sequencing and a new era of medicine.
Gut. 2013 Jun;62(6):920-32. doi: 10.1136/gutjnl-2011-301935. Epub 2012 May 1. PubMed PMID: 22550129; PubMed Central PMCID: PMC5105595.
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Genome-wide association analyses in East Asians identify new susceptibility loci for colorectal cancer.
Nat Genet. 2013 Feb;45(2):191-6. doi: 10.1038/ng.2505. Epub 2012 Dec 23. PubMed PMID: 23263487; PubMed Central PMCID: PMC3679924.
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Gender-stratified gene and gene-treatment interactions in smoking cessation.
Pharmacogenomics J. 2012 Dec;12(6):521-32. doi: 10.1038/tpj.2011.30. Epub 2011 Aug 2. PubMed PMID: 21808284; PubMed Central PMCID: PMC3208134.
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DRD1 associations with smoking abstinence across slow and normal nicotine metabolizers.
Pharmacogenet Genomics. 2012 Jul;22(7):551-4. doi: 10.1097/FPC.0b013e3283539062. PubMed PMID: 22495174; PubMed Central PMCID: PMC3376177.
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Further replication studies of the EVE Consortium meta-analysis identifies 2 asthma risk loci in European Americans.
J Allergy Clin Immunol. 2012 Dec;130(6):1294-301. doi: 10.1016/j.jaci.2012.07.054. Epub 2012 Oct 4. PubMed PMID: 23040885; PubMed Central PMCID: PMC3666859.
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Analysis and optimal design for association studies using next-generation sequencing with case-control pools.
Genet Epidemiol. 2012 Dec;36(8):870-81. doi: 10.1002/gepi.21681. Epub 2012 Sep 12. PubMed PMID: 22972696; PubMed Central PMCID: PMC4139478.
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Joint analysis for integrating two related studies of different data types and different study designs using hierarchical modeling approaches.
Hum Hered. 2012;74(2):83-96. doi: 10.1159/000345181. Epub 2013 Jan 18. PubMed PMID: 23343600; PubMed Central PMCID: PMC4106669.
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Cigarette smoking and subtypes of bladder cancer.
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A genome-wide meta-analysis of nodular sclerosing Hodgkin lymphoma identifies risk loci at 6p21.32.
Blood. 2012 Jan 12;119(2):469-75. doi: 10.1182/blood-2011-03-343921. Epub 2011 Nov 15. PubMed PMID: 22086417; PubMed Central PMCID: PMC3257012.
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Vitamin D levels in Hispanics with multiple sclerosis.
J Neurol. 2012 Dec;259(12):2565-70. doi: 10.1007/s00415-012-6537-z. Epub 2012 May 16. PubMed PMID: 22588255;
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Smoking cessation pharmacogenetics: analysis of varenicline and bupropion in placebo-controlled clinical trials.
Neuropsychopharmacology. 2012 Feb;37(3):641-50. doi: 10.1038/npp.2011.232. Epub 2011 Nov 2. PubMed PMID: 22048466; PubMed Central PMCID: PMC3260990.
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Genome-wide search for gene-gene interactions in colorectal cancer.
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Underlying genetic structure impacts the association between CYP2B6 polymorphisms and response to efavirenz and nevirapine.
AIDS. 2012 Oct 23;26(16):2097-106. doi: 10.1097/QAD.0b013e3283593602. PubMed PMID: 22951632; PubMed Central PMCID: PMC3940150.
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Varenicline for smoking cessation: nausea severity and variation in nicotinic receptor genes.
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Meta-analysis of new genome-wide association studies of colorectal cancer risk.
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Incorporating prior biologic information for high-dimensional rare variant association studies.
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Network-assisted investigation of combined causal signals from genome-wide association studies in schizophrenia.
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Pharmacogenetic association of the galanin receptor (GALR1) SNP rs2717162 with smoking cessation.
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Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk.
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A bias-reducing pathway enrichment analysis of genome-wide association data confirmed association of the MHC region with schizophrenia.
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Schizophrenia susceptibility alleles are enriched for alleles that affect gene expression in adult human brain.
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Using extreme phenotype sampling to identify the rare causal variants of quantitative traits in association studies.
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Genotype-environment interactions in microsatellite stable/microsatellite instability-low colorectal cancer: results from a genome-wide association study.
Cancer Epidemiol Biomarkers Prev. 2011 May;20(5):758-66. doi: 10.1158/1055-9965.EPI-10-0675. Epub 2011 Feb 25. PubMed PMID: 21357381; PubMed Central PMCID: PMC3089660.
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Incorporating model uncertainty in detecting rare variants: the Bayesian risk index.
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Sample size requirements to detect gene-environment interactions in genome-wide association studies.
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Lower risk in parous women suggests that hormonal factors are important in bladder cancer etiology.
Cancer Epidemiol Biomarkers Prev. 2011 Jun;20(6):1156-70. doi: 10.1158/1055-9965.EPI-11-0017. Epub 2011 Apr 14. PubMed PMID: 21493870; PubMed Central PMCID: PMC3312020.
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Variation in folate pathway genes and distal colorectal adenoma risk: a sigmoidoscopy-based case-control study.
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A systems biology network model for genetic association studies of nicotine addiction and treatment.
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Snagger: a user-friendly program for incorporating additional information for tagSNP selection.
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The effect of montelukast and low-dose theophylline on cardiovascular disease risk factors in asthmatics.
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Comprehensive evaluation of the association between prostate cancer and genotypes/haplotypes in CYP17A1, CYP3A4, and SRD5A2.
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A survey of current Bayesian gene mapping methods.
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